Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six.
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Structure of the TRPA1 ion channel suggests regulatory mechanismsThermotaxis, circadian rhythms, and TRP channels in DrosophilaSpecies-specific temperature sensitivity of TRPA1How the TRPA1 receptor transmits painful stimuli: Inner workings revealed by electron cryomicroscopyNociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain PathologiesThe pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazoleInformation processing in the CNS: a supramolecular chemistry?Molecular mechanisms of temperature adaptationN-terminal tetrapeptide T/SPLH motifs contribute to multimodal activation of human TRPA1 channelIsoform-specific modulation of the chemical sensitivity of conserved TRPA1 channel in the major honeybee ectoparasitic mite, Tropilaelaps mercedesaeTRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity.Are sensory TRP channels biological alarms for lipid peroxidation?Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domainUnfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.Use Dependence of Heat Sensitivity of Vanilloid Receptor TRPV2.TRPA1 Channels in Drosophila and Honey Bee Ectoparasitic Mites Share Heat Sensitivity and Temperature-Related Physiological FunctionsLow-cost functional plasticity of TRPV1 supports heat tolerance in squirrels and camels.Sensory TRP channels: the key transducers of nociception and pain.Evolutionary dynamics of metazoan TRP channels.Ethyl Vanillin Activates TRPA1.Thermosensation and longevity.Genetic variants affecting human TRPA1 or TRPM8 structure can be classified in vitro as 'well expressed', 'poorly expressed' or 'salvageable'.The N-terminal Ankyrin Repeat Domain Is Not Required for Electrophile and Heat Activation of the Purified Mosquito TRPA1 Receptor.Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity.Calmodulin is responsible for Ca2+-dependent regulation of TRPA1 ChannelsTrpA1 activation in peripheral sensory neurons underlies the ionic basis of pain hypersensitivity in response to vinca alkaloids.TRPA1 channels: molecular sentinels of cellular stress and tissue damage.Global versus local mechanisms of temperature sensing in ion channels.Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception.Regulation of Pain and Itch by TRP Channels.Sensitivities of Two Zebrafish TRPA1 Paralogs to Chemical and Thermal Stimuli Analyzed in Heterologous Expression Systems.HsTRPA of the Red Imported Fire Ant, Solenopsis invicta, Functions as a Nocisensor and Uncovers the Evolutionary Plasticity of HsTRPA Channels.TRPs et al.: a molecular toolkit for thermosensory adaptations.TRPA1 expression levels and excitability brake by KV channels influence cold sensitivity of TRPA1-expressing neurons.Chemical Activation of Sensory TRP Channels
P2860
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P2860
Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Directionality of temperature ...... tations in ankyrin repeat six.
@en
type
label
Directionality of temperature ...... tations in ankyrin repeat six.
@en
prefLabel
Directionality of temperature ...... tations in ankyrin repeat six.
@en
P2093
P2860
P1433
P1476
Directionality of temperature ...... tations in ankyrin repeat six.
@en
P2093
Ardem Patapoutian
Breanna Kalmeta
Hans Moldenhauer
Jason O Sosa-Pagán
Jörg Grandl
Michael Bandell
Raman Goyal
Ramon Latorre
Sairam Jabba
P2860
P304
P356
10.1016/J.NEURON.2014.04.016
P407
P577
2014-05-08T00:00:00Z