Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida lusitaniae.
about
A functional variomics tool for discovering drug-resistance genes and drug targets.Antagonistic changes in sensitivity to antifungal drugs by mutations of an important ABC transporter gene in a fungal pathogenCalcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniaeThe molecular mechanism of a cis-regulatory adaptation in yeastFitness trade-offs restrict the evolution of resistance to amphotericin BDrug resistance in leishmaniasisAntigenic and phenotypic variations in fungiSphingolipid biosynthetic pathway genes FEN1 and SUR4 modulate amphotericin B resistance.Comparative genomics allowed the identification of drug targets against human fungal pathogens.Aspergillus fumigatus C-5 sterol desaturases Erg3A and Erg3B: role in sterol biosynthesis and antifungal drug susceptibility.Plasma Membrane Proteolipid 3 Protein Modulates Amphotericin B Resistance through Sphingolipid Biosynthetic Pathway.Stepwise emergence of azole, echinocandin and amphotericin B multidrug resistance in vivo in Candida albicans orchestrated by multiple genetic alterations.In search of the holy grail of antifungal therapyCell Wall Changes in Amphotericin B-Resistant Strains from Candida tropicalis and Relationship with the Immune Responses Elicited by the HostThe Role of Signaling via Aqueous Pore Formation in Resistance Responses to Amphotericin BChromosome 5 monosomy of Candida albicans controls susceptibility to various toxic agents, including major antifungalsCandida albicans hyphal formation and virulence assessed using a Caenorhabditis elegans infection model.Phenotypic Switching in Fungi.The Candida pathogenic species complex.The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulenceAntifungals: Mechanism of Action and Drug Resistance.Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus.Rapid identification of yeast by fluorescence in situ hybridisation from broth and blood cultures.Polyene susceptibility is dependent on nitrogen source in the opportunistic pathogen Candida albicans.Antifungal resistance and new strategies to control fungal infections.Contributions of the response regulators Ssk1p and Skn7p in the pseudohyphal development, stress adaptation, and drug sensitivity of the opportunistic yeast Candida lusitaniae.Effects of Aspirin as an Anti-inflammatory Drug on Azole-resistant Candida glabrata In Vitro.Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis.ERG6 gene deletion modifies Kluyveromyces lactis susceptibility to various growth inhibitors.Trans-chalcone and quercetin down-regulate fatty acid synthase gene expression and reduce ergosterol content in the human pathogenic dermatophyte Trichophyton rubrum.Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes.Differential involvement of histidine kinase receptors in pseudohyphal development, stress adaptation, and drug sensitivity of the opportunistic yeast Candida lusitaniae.Dependence of vacuole disruption and independence of potassium ion efflux in fungicidal activity induced by combination of amphotericin B and allicin against Saccharomyces cerevisiae.Reduced susceptibility to polyenes associated with a missense mutation in the ERG6 gene in a clinical isolate of Candida glabrata with pseudohyphal growth.Drug resistance and treatment failure in leishmaniasis: A 21st century challenge.Quantitation of ergosterol content and gene expression profile of ERG11 gene in fluconazole-resistant Candida albicans.Enhanced Efflux Pump Activity in Old Candida glabrata.
P2860
Q27932829-FF268EBF-BC61-4A21-ABA8-E9CD299A325CQ28474724-DB70BA40-D881-448D-BD85-61C5D22B16EFQ28483234-EAECC1C1-C859-4B5B-B7EF-DB6AC76F1A99Q28533667-F9C34E4A-1A97-4DC6-AC1C-F380CE43F7F2Q28534687-E355AECB-41D1-4FC3-ACEC-799C377E578BQ29616242-30C0F0EB-4389-45A9-B5E8-B19E13A9A46DQ33505448-1F0F77AF-C742-4E97-BDF2-6F951C4DD844Q33622748-584500CB-14EA-4591-A66E-9F88142B1420Q33805404-93CE26F2-5A88-410B-A79D-39D67A2E5B8BQ34352270-88A7E296-16E7-49D0-BE9A-29E8A17F1EADQ35596158-9EE74E19-5FB8-4B91-A746-9CB7BC10271BQ36008037-580349EB-BD6F-4E9F-AB2C-5088DE7CC326Q36672181-11059575-4356-49D6-AF77-366D7DD965D1Q36729978-3C6064C3-96E3-4E41-AD4F-69751D74C2DBQ37203821-D0AC14CD-9E4F-4A89-A420-3356AE1EF1F8Q37263898-E0BCBF15-AFD1-46BB-884F-66325FE75233Q37410095-8246A614-EED8-49C8-99B6-A8FADDB8BE62Q37600634-EBAB5DB0-BAC7-460E-AEE5-8856A76012B4Q38245727-AA40E004-5659-4823-9D30-38943C1E8938Q38453030-B96DF91E-5B14-42BA-88A1-87E372E3C47BQ38684281-0A37AB83-1EF6-4DDC-AAEF-5066A33996C9Q38711698-B3226A63-6FA5-4F2F-8AC5-5AF2A191A6BCQ39012335-47C44858-7EB6-4DB9-9F2E-4397F47C3FC9Q39040879-4D839BEE-FA31-4D2E-822A-29EF03E2D040Q39751373-27039C23-1467-453E-8757-3EFE44B322ABQ39756062-973B556E-DF0A-40E6-97A5-F1AB5271CE23Q39791323-D1A0C4FE-67A8-4C3D-BEB0-46BAB5B0BBAAQ40166236-12B75E37-65B5-4036-B8F5-E21884979666Q40565750-93294AD7-7C85-4A16-9CE4-1292B74D772CQ42006723-4C2DA6D9-A57E-46CC-91AB-7FA9DA265A29Q42477429-58F2415B-D1C8-40FC-B438-9D3155FECA5AQ42628406-7EEEF28D-D83D-4E88-AD13-38D62B0E69EAQ42860927-D3413A0D-87AF-434C-8EBB-205AA4F5B565Q42948674-39616AFA-D4CD-4392-9BCF-046805FD38CFQ46380663-7C6EEC42-1BC9-4231-BF9F-B7A938E496E7Q47179899-A7CA9AAC-91DF-4208-B37E-456062094CDAQ50134191-C9075339-F247-4CFE-BAEE-08F1F53F96B7
P2860
Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida lusitaniae.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Disruption of ergosterol biosy ...... ricin B in Candida lusitaniae.
@en
type
label
Disruption of ergosterol biosy ...... ricin B in Candida lusitaniae.
@en
prefLabel
Disruption of ergosterol biosy ...... ricin B in Candida lusitaniae.
@en
P2860
P1476
Disruption of ergosterol biosy ...... ricin B in Candida lusitaniae.
@en
P2093
Christina M Hull
Laura Y Young
P2860
P304
P356
10.1128/AAC.47.9.2717-2724.2003
P407
P577
2003-09-01T00:00:00Z