HLA-DR-presented peptide repertoires derived from human monocyte-derived dendritic cells pulsed with blood coagulation factor VIII.
about
Dangerous liaisons: how the immune system deals with factor VIIIOxidized low-density lipoprotein, OXPAPC, corrects defects in maturation and cytokine secretion of peripheral blood dendritic cells from sepsis patients.Factor VIII gene variants and inhibitor risk in African American hemophilia A patientsSampling From the Proteome to the Human Leukocyte Antigen-DR (HLA-DR) Ligandome Proceeds Via High SpecificityCD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice.The human leukocyte antigen-presented ligandome of B lymphocytes.von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.Mass spectrometry-assisted study reveals that lysine residues 1967 and 1968 have opposite contribution to stability of activated factor VIII.Transmembrane TNF-dependent uptake of anti-TNF antibodies.Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice.Limited promiscuity of HLA-DRB1 presented peptides derived of blood coagulation factor VIII.T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire.Distinct roles of Ser-764 and Lys-773 at the N terminus of von Willebrand factor in complex assembly with coagulation factor VIIIIn silico calculated affinity of FVIII-derived peptides for HLA class II alleles predicts inhibitor development in haemophilia A patients with missense mutations in the F8 gene.Comparative profiling of HLA-DR and HLA-DQ associated factor VIII peptides presented by monocyte-derived dendritic cells.Models for assessing immunogenicity and efficacy of new therapeutics for the treatment of haemophilia.High-throughput and Sensitive Immunopeptidomics Platform Reveals Profound Interferonγ-Mediated Remodeling of the Human Leukocyte Antigen (HLA) Ligandome.Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ.Storage-Induced Platelet Apoptosis Is a Potential Risk Factor for Alloimmunization Upon Platelet Transfusion.
P2860
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P2860
HLA-DR-presented peptide repertoires derived from human monocyte-derived dendritic cells pulsed with blood coagulation factor VIII.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
HLA-DR-presented peptide reper ...... blood coagulation factor VIII.
@en
type
label
HLA-DR-presented peptide reper ...... blood coagulation factor VIII.
@en
prefLabel
HLA-DR-presented peptide reper ...... blood coagulation factor VIII.
@en
P2093
P2860
P356
P1476
HLA-DR-presented peptide reper ...... blood coagulation factor VIII.
@en
P2093
Alexander B Meijer
Anja ten Brinke
Eszter Herczenik
Jan Voorberg
Koen Mertens
Simon D van Haren
P2860
P304
M110.002246
P356
10.1074/MCP.M110.002246
P577
2011-04-05T00:00:00Z