The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes.
about
PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitryRoles of RNA-Binding Proteins in DNA Damage ResponseRNA helicases in splicingCoupling pre-mRNA processing to transcription on the RNA factory assembly lineThe SPF27 homologue Num1 connects splicing and kinesin 1-dependent cytoplasmic trafficking in Ustilago maydisRSR-2, the Caenorhabditis elegans ortholog of human spliceosomal component SRm300/SRRM2, regulates development by influencing the transcriptional machineryQuality control of spliced mRNAs requires the shuttling SR proteins Gbp2 and Hrb1.The poly(A)-binding protein Nab2 functions in RNA polymerase III transcriptionThe role of TREX in gene expression and diseaseNuclear export of messenger RNASub1 associates with Spt5 and influences RNA polymerase II transcription elongation rateRecruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase IIUbiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life spanA Sub-Element in PRE enhances nuclear export of intronless mRNAs by recruiting the TREX complex via ZC3H18Proteomic analysis reveals CACN-1 is a component of the spliceosome in Caenorhabditis elegans.The RNA polymerase II CTD coordinates transcription and RNA processing.Sororin pre-mRNA splicing is required for proper sister chromatid cohesion in human cells.Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy.NTR1 is required for transcription elongation checkpoints at alternative exons in ArabidopsisSmall kinetochore associated protein (SKAP) promotes UV-induced cell apoptosis through negatively regulating pre-mRNA processing factor 19 (Prp19).Structural characterization of the Saccharomyces cerevisiae THO complex by small-angle X-ray scatteringHITS-CLIP analysis uncovers a link between the Kaposi's sarcoma-associated herpesvirus ORF57 protein and host pre-mRNA metabolismRegulation of ribosomal RNA production by RNA polymerase I: does elongation come first?CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex.The spliceosome-activating complex: molecular mechanisms underlying the function of a pleiotropic regulatorXAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE.The C-Terminal SynMuv/DdDUF926 Domain Regulates the Function of the N-Terminal Domain of DdNKAP.Evidence that a consensus element found in naturally intronless mRNAs promotes mRNA exportUnraveling molecular effects of ADAR1 overexpression in HEK293T cells by label-free quantitative proteomicsHuman TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I.Requirement for highly efficient pre-mRNA splicing during Drosophila early embryonic development.The yeast THO complex forms a 5-subunit assembly that directly interacts with active chromatin.New insights into pre-mRNA processing factor 19: A multi-faceted protein in humans.Pre-mRNA processing factors meet the DNA damage response.Co-transcriptional mRNP formation is coordinated within a molecular mRNP packaging station in S. cerevisiaeHow gene expression in fast-proliferating cells keeps pace.Quick or quality? How mRNA escapes nuclear quality control during stress.Integration of mRNP formation and export.Exploring the Human-Nipah Virus Protein-Protein Interactome.The THO complex cooperates with the nuclear RNA surveillance machinery to control small nucleolar RNA expression.
P2860
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P2860
The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The Prp19 complex is a novel t ...... ccupancy at transcribed genes.
@en
type
label
The Prp19 complex is a novel t ...... ccupancy at transcribed genes.
@en
prefLabel
The Prp19 complex is a novel t ...... ccupancy at transcribed genes.
@en
P2860
P356
P1433
P1476
The Prp19 complex is a novel t ...... occupancy at transcribed genes
@en
P2093
Martin Seizl
Sittinan Chanarat
P2860
P304
P356
10.1101/GAD.623411
P577
2011-05-16T00:00:00Z