Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents.
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TRPA1 mediates formalin-induced painA study comparing the actions of gabapentin and pregabalin on the electrophysiological properties of cultured DRG neurones from neonatal ratsMechanisms of the gabapentinoids and α 2 δ-1 calcium channel subunit in neuropathic painNovel therapeutic strategies for alcohol and drug addiction: focus on GABA, ion channels and transcranial magnetic stimulationGabapentin inhibits excitatory synaptic transmission in the hyperalgesic spinal cordPregabalin may represent a novel class of anxiolytic agents with a broad spectrum of activityBlock by gabapentin of the facilitation of glutamate release from rat trigeminal nucleus following activation of protein kinase C or adenylyl cyclaseAntiallodynic effect of pregabalin in rat models of sympathetically maintained and sympathetic independent neuropathic painModeling nociception in zebrafish: a way forward for unbiased analgesic discoveryCentral Mechanisms Mediating Thrombospondin-4-induced Pain States.3-substituted GABA analogs with central nervous system activity: a review.Improving the translation of analgesic drugs to the clinic: animal models of neuropathic pain.The effects of gabapentin pretreatment on brain injury induced by focal cerebral ischemia/reperfusion in the rat.Gabapentin: pharmacology and its use in pain management.Palliative care--new approaches to the problem of suffering.Pregabalin in acute and chronic pain.A comparative study of pre-operative oral clonidine and pregabalin on post-operative analgesia after spinal anesthesia.Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin.Centrally acting agents and visceral sensitivity.Alpha 2 Delta (α(2)δ) Ligands, Gabapentin and Pregabalin: What is the Evidence for Potential Use of These Ligands in Irritable Bowel SyndromeRole of descending noradrenergic system and spinal alpha2-adrenergic receptors in the effects of gabapentin on thermal and mechanical nociception after partial nerve injury in the mouseSpinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury.Emerging drugs in migraine treatment.Gabapentin in the treatment of neuropathic pain.Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain.The effects of intrathecal and systemic gabapentin on spinal substance P release.Drug management of visceral pain: concepts from basic research.Effect of a second-generation alpha2delta ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome.Nerve injury-induced calcium channel alpha-2-delta-1 protein dysregulation leads to increased pre-synaptic excitatory input into deep dorsal horn neurons and neuropathic allodyniaThe antiallodynic action of pregabalin in neuropathic pain is independent from the opioid system.Spontaneous Chronic Pain After Experimental Thoracotomy Revealed by Conditioned Place Preference: Morphine Differentiates Tactile Evoked Pain From Spontaneous PainFibromyalgia syndrome, idiopathic widespread persistent pain or syndrome of myalgic encephalomyelopathy (SME): what is its nature?(-)-Trans-Δ(9)-Tetrahydrocannabinol-Like Discriminative-Stimulus Effects of Gabapentin in Cannabis UsersComparative effects of α2δ-1 ligands in mouse models of colonic hypersensitivity.Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model.Calcium channel α2δ1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis.Differential upregulation in DRG neurons of an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury.Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysisAdjuvant analgesics in acute pain.Improving acute pain management in emergency medicine.
P2860
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P2860
Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Gabapentin (neurontin) and S-( ...... ctive antihyperalgesic agents.
@en
type
label
Gabapentin (neurontin) and S-( ...... ctive antihyperalgesic agents.
@en
prefLabel
Gabapentin (neurontin) and S-( ...... ctive antihyperalgesic agents.
@en
P2093
P356
P1476
Gabapentin (neurontin) and S-( ...... ctive antihyperalgesic agents.
@en
P2093
P304
P356
10.1038/SJ.BJP.0701320
P407
P577
1997-08-01T00:00:00Z