Complement factor H-related hybrid protein deregulates complement in dense deposit disease. - Wikidata - awgldk - TriplyDB

Complement factor H-related hybrid protein deregulates complement in dense deposit disease.

Complement factor H-related hybrid protein deregulates complement in dense deposit disease.

http://www.wikidata.org/entity/Q41826438

about

Reclassification of membranoproliferative glomerulonephritis: Identification of a new GN: C3GN Complement System Part II: Role in Immunity Factor H Family Proteins in Complement Evasion of Microorganisms.New insights into disease-specific absence of complement factor H related protein C in mouse models of spontaneous autoimmune diseases Defining the complement biomarker profile of C3 glomerulopathy Annexin A2 Enhances Complement Activation by Inhibiting Factor H Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.The Genetics of Ultra-Rare Renal Disease.Kidney Disease Caused by Dysregulation of the Complement Alternative Pathway: An Etiologic Approach.Rituximab for Treatment of Membranoproliferative Glomerulonephritis and C3 Glomerulopathies.Retinal disease in the C3 glomerulopathies and the risk of impaired vision.From orphan drugs to adopted therapies: Advancing C3-targeted intervention to the clinical stage.The complement factor H-related proteins.C3 glomerulopathy.Complement C3-Targeted Therapy: Replacing Long-Held Assertions with Evidence-Based Discovery.Circulating complement factor H-related proteins 1 and 5 correlate with disease activity in IgA nephropathy.Factor H-related protein 5 interacts with pentraxin 3 and the extracellular matrix and modulates complement activation.Update on C3 glomerulopathy.Complement Factor H-Related 5-Hybrid Proteins Anchor Properdin and Activate Complement at Self-Surfaces.Rare Variants in the Complement Factor H-Related Protein 5 Gene Contribute to Genetic Susceptibility to IgA Nephropathy.The Murine Factor H-Related Protein FHR-B Promotes Complement Activation Kidney transplant outcomes in familial C3 glomerulopathy.Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma.C4 Nephritic Factors in C3 Glomerulopathy: A Case Series.The MFHR1 Fusion Protein Is a Novel Synthetic Multitarget Complement Inhibitor with Therapeutic Potential.Diseases of complement dysregulation-an overview.Functional Characterization of the Disease-Associated N-Terminal Complement Factor H Mutation W198R.An Engineered Complement Factor H Construct for Treatment of C3 Glomerulopathy.C3 Glomerulopathy.Management of hemolytic uremic syndrome Thrombotic microangiopathy after renal transplantation: Current insights in and recurrent disease Reference Intervals of Factor H and Factor H-Related Proteins in Healthy Children

P2860

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P2860

Complement factor H-related hybrid protein deregulates complement in dense deposit disease.

http://www.wikidata.org/entity/Q41826438

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Complement factor H-related hy ...... ment in dense deposit disease.

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type

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Complement factor H-related hy ...... ment in dense deposit disease.

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Complement factor H-related hy ...... ment in dense deposit disease.

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Journal of Clinical Investigation

P1476

Complement factor H-related hy ...... ment in dense deposit disease.

@en

P2093

Andrea Hartmann

http://www.w3.org/2001/XMLSchema#string

Barbara Uzonyi

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Christian Hugo

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Christine Skerka

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Hannes U Eberhardt

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Kerstin Amann

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Michael Kirschfink

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Michael Wiesener

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Qian Chen

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Tim Goodship

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P2860

Human factor H deficiency. Mutations in framework cysteine residues and block in H protein secretion and intracellular catabolism

Molecular cloning of a human serum protein structurally related to complement factor H

Deletion of Lys224 in regulatory domain 4 of Factor H reveals a novel pathomechanism for dense deposit disease (MPGN II)

Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification

Genetic applications of an inverse polymerase chain reaction

Structures of C3b in complex with factors B and D give insight into complement convertase formation

Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis

Eculizumab for dense deposit disease and C3 glomerulonephritis

Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease)

Compstatin: a complement inhibitor on its way to clinical application

P304

145-155

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scholarly article

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10.1172/JCI71866

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1

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124

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Andrea Buettner

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2013-12-16T00:00:00Z

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24334459

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3871254

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