Structure-Activity Relationship Studies of 3-epi-Deoxynegamycin Derivatives as Potent Readthrough Drug Candidates.

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Chemotherapeutics overcoming nonsense mutation-associated genetic diseases: medicinal chemistry of negamycin.Structure-Activity Relationship Study of Leucyl-3-epi-deoxynegamycin for Potent Premature Termination Codon Readthrough.

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Structure-Activity Relationship Studies of 3-epi-Deoxynegamycin Derivatives as Potent Readthrough Drug Candidates.

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2015 nî lūn-bûn

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Structure-Activity Relationshi ...... t Readthrough Drug Candidates.

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Structure-Activity Relationshi ...... t Readthrough Drug Candidates.

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Structure-Activity Relationshi ...... t Readthrough Drug Candidates.

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Structure-Activity Relationshi ...... t Readthrough Drug Candidates.

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Akihiro Taguchi

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Fumika Yakushiji

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Keisuke Hamada

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Kentaro Takayama

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Masaya Kotake

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Saori Murakami

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Suguru Aita

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Yoshio Hayashi

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Nonsense-mediated mRNA decay in health and disease

Germinal mosaicism increases the recurrence risk for 'new' Duchenne muscular dystrophy mutations

Aminoglycosides: nephrotoxicity

Correction of genetic disease by making sense from nonsense.

Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice

PTC124 targets genetic disorders caused by nonsense mutations.

Readthrough of premature termination codons in the adenomatous polyposis coli gene restores its biological activity in human cancer cells

Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system

Randomized, double-blind six-month trial of prednisone in Duchenne's muscular dystrophy.

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689-694

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scholarly article

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10.1021/ACSMEDCHEMLETT.5B00121

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P478

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2015-05-11T00:00:00Z

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26101575

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4468409

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Structure-Activity Relationship Studies of 3-epi-Deoxynegamycin Derivatives as Potent Readthrough Drug Candidates.

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Structure-Activity Relationship Studies of 3-epi-Deoxynegamycin Derivatives as Potent Readthrough Drug Candidates.

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P2093

P2860

P304

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P356

P433

P478

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P698

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