The crystal structure of PfFabZ, the unique beta-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum.
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Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ)Campylobacter jejuni fatty acid synthase II: Structural and functional analysis of β-hydroxyacyl-ACP dehydratase (FabZ)Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic PathwaySAD phasing using iodide ions in a high-throughput structural genomics environmentInsights into the substrate specificity of a thioesterase Rv0098 of mycobacterium tuberculosis through X-ray crystallographic and molecular dynamics studiesHigh resolution crystal structure of Clostridium propionicum β-alanyl-CoA:ammonia lyase, a new member of the "hot dog fold" protein superfamilyUsing modern tools to probe the structure-function relationship of fatty acid synthasesStructure and function of Rv0130, a conserved hypothetical protein from Mycobacterium tuberculosisAnalysis of proteins with the 'hot dog' fold: prediction of function and identification of catalytic residues of hypothetical proteins.Targeting the Lipid Metabolic Pathways for the Treatment of Malaria.Recent developments in the antiprotozoal and anticancer activities of the 2-alkynoic fatty acids.2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes.Modeling holo-ACP:DH and holo-ACP:KR complexes of modular polyketide synthases: a docking and molecular dynamics study.Molecular basis for the inhibition of β-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.Active site comparisons and catalytic mechanisms of the hot dog superfamily.Fungal naphtho-γ-pyrones: Potent antibiotics for drug-resistant microbial pathogens.Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis.Recent advances in inhibitors of bacterial fatty acid synthesis type II (FASII) system enzymes as potential antibacterial agents.From crystal to compound: structure-based antimalarial drug discovery.Antiplasmodial drug targets: a patent review (2000 - 2013).Sunflower (Helianthus annuus) fatty acid synthase complex: β-hydroxyacyl-[acyl carrier protein] dehydratase genes.A high yield optimized method for the production of acylated ACPs enabling the analysis of enzymes involved in P. falciparum fatty acid biosynthesis.Identification and Phenotypic Characterization of ZEBRA LEAF16 Encoding a β-Hydroxyacyl-ACP Dehydratase in Rice.
P2860
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P2860
The crystal structure of PfFabZ, the unique beta-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The crystal structure of PfFab ...... esis of Plasmodium falciparum.
@en
type
label
The crystal structure of PfFab ...... esis of Plasmodium falciparum.
@en
prefLabel
The crystal structure of PfFab ...... esis of Plasmodium falciparum.
@en
P2093
P2860
P356
P1433
P1476
The crystal structure of PfFab ...... hesis of Plasmodium falciparum
@en
P2093
Dirk Kostrewa
Fritz K Winkler
Leonardo Scapozza
Remo Perozzo
P2860
P304
P356
10.1110/PS.051373005
P50
P577
2005-06-01T00:00:00Z