Methylation-mediated deamination of 5-methylcytosine appears to give rise to mutations causing human inherited disease in CpNpG trinucleotides, as well as in CpG dinucleotides.
about
The role of methylation in the intrinsic dynamics of B- and Z-DNANutlin-3a, an MDM2 antagonist and p53 activator, helps to preserve the replicative potential of cancer cells treated with a genotoxic dose of resveratrolDNA Methylation: Insights into Human EvolutionGenetic divergence between freshwater and marine morphs of alewife (Alosa pseudoharengus): a 'next-generation' sequencing analysisMethyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus ZtaOligodeoxynucleotides Can Transiently Up- and Downregulate CHS Gene Expression in Flax by Changing DNA Methylation in a Sequence-Specific Manner.Genome wide SNP discovery, analysis and evaluation in mallard (Anas platyrhynchos).Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells.Genetic and phenotypic diversity of NHE6 mutations in Christianson syndrome.On the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease.Population-level consequences of complementary sex determination in a solitary parasitoid.The somatic autosomal mutation matrix in cancer genomes.Exploring the somatic NF1 mutational spectrum associated with NF1 cutaneous neurofibromasPrevalence of Titin Truncating Variants in General Population.Depletion of CpG Dinucleotides in Papillomaviruses and Polyomaviruses: A Role for Divergent Evolutionary Pressures.Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the hostRole for tissue-dependent methylation differences in the expression of FOXE1 in nontumoral thyroid glandsRecurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes.Nuclear reprogramming and its role in vascular smooth muscle cells.Adaptation or malignant transformation: the two faces of epigenetically mediated response to stress.Preventive DNA repair by sanitizing the cellular (deoxy)nucleoside triphosphate pool.KCNT1 mutations in seizure disorders: the phenotypic spectrum and functional effects.Transgenerational inheritance: Models and mechanisms of non-DNA sequence-based inheritance.The Val142Ile transthyretin cardiac amyloidosis: more than an Afro-American pathogenic variant.8-Oxo-7,8-dihydroguanine, friend and foe: Epigenetic-like regulator versus initiator of mutagenesis.Cysteamine revisited: repair of arginine to cysteine mutations.Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma.Expanding the DNA alphabet in the fruit fly: uracil enrichment in genomic DNA.DNA mutation motifs in the genes associated with inherited diseases.Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially.Cutaneous malignant melanoma incidences analyzed worldwide by sex, age, and skin type over personal Ultraviolet-B dose shows no role for sunburn but implies one for Vitamin D3.DNA methylation pattern of CALCA in preterm neonates with bacterial sepsis as a putative epigenetic biomarker.A Recurrent De Novo Variant in NACC1 Causes a Syndrome Characterized by Infantile Epilepsy, Cataracts, and Profound Developmental Delay.Spectrum of RB1 mutations identified in 403 retinoblastoma patients.Evolving paradigms for the biological response to low dose ionizing radiation; the role of epigenetics.Untangling the most probable role for vitamin D3 in autism.Comparative analysis of germline and somatic microlesion mutational spectra in 17 human tumor suppressor genes.Two novel recessive mutations in KRT14 identified in a cohort of 21 Spanish families with epidermolysis bullosa simplex.Epigenetic regulation of inflammation in stroke.
P2860
Q21134614-37BBD66A-9407-42C3-A253-414007BF14D7Q24595171-7FAD0EBD-593A-46F1-A136-4D25EA1BD0A5Q26776426-15C2574B-9F93-41DE-859D-D120CD3FC2FFQ28731289-B259614E-D0A5-402A-85E2-4B142B4C44C8Q33557545-F62FFC1A-A601-4D99-B2EA-BD9BE1867ED2Q33679370-F4826294-EE0B-4E14-B6B0-6E08B5AA2123Q33848481-C1D82CD7-9CBB-44B3-9D67-371E774FF8E6Q34695467-E226E119-90D1-4E00-9559-9EA4FCFAFA48Q35007161-2A625D8F-97BF-4CEF-8AE8-F914CB281EB4Q35226155-AC2F31A2-89F3-40C6-B410-8E8BCE017943Q35646802-312DE800-1ED8-4046-A72E-9B5CB06587CCQ35829550-A4E6FF04-081F-4D9E-8A30-07CAB1972D71Q35837640-316F546A-FBB7-4658-9969-040D38800C0BQ35877860-8B5BE7EA-E7BC-426D-B39D-9E01156FE985Q36257457-517CD2A5-21D1-4869-A1C2-B23C68D6DE0AQ36257990-0AA086C6-9E97-43E9-B3A6-A8AA14234B51Q37309797-3EB270F6-750B-450B-8FCF-5BCA26F1E4D5Q37342031-73AFF4BE-E0EE-49D8-9326-0E75683FFA79Q38123734-2F518F60-0411-4566-84B0-815440AA6779Q38159699-2B460EE2-0050-4C6B-9811-F931C03FE6EDQ38232763-6BAFFB51-4201-475C-B5FF-BD30E8F322F7Q38689167-689FC07D-1651-4D73-83D8-A3C809A77EA5Q39009429-E1733A93-5E5C-467A-ADAC-4E9688EAF3D0Q39305292-B30E1BE9-2AFE-477C-AFF8-0A1D7677A8F2Q39383987-AEA028DF-77F2-47C0-AFB1-EAA20E4973B8Q39393159-3523EEC3-1153-4F55-9F26-5BB2B7B49102Q40151513-58F192D9-ECDA-44FE-9904-F5E6B27575C3Q40916036-934DA7C7-267A-4447-89BB-7AD205C4DB41Q41216018-E92D4DF7-A7EA-4EE5-94C1-8F02CD1B2E38Q41414883-653750D0-ED33-4428-A21D-D87ED1F34D79Q41725092-1BAB7E04-FFFC-4601-A3E2-F720BF70F7AAQ41891410-3EC8771E-4656-478F-AC37-16A0A1ED7569Q41920971-330671C9-B164-41CE-A879-AEC77DF00C50Q46194694-BF90A2CC-5DB9-4D20-AFB7-4C59BD4A82B8Q47441747-3012FCD2-E5D4-42A8-863A-B3BA4F37C918Q50301196-D28A1894-5071-45EF-9D9D-8593E9E8567DQ53288810-210FBA95-1744-4976-91DF-8CFFAAB28D1FQ54368660-78290825-3E27-46F2-979B-D35E26C1905BQ55209717-EACB33C2-10A3-44B5-8806-605AE7727F30
P2860
Methylation-mediated deamination of 5-methylcytosine appears to give rise to mutations causing human inherited disease in CpNpG trinucleotides, as well as in CpG dinucleotides.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Methylation-mediated deaminati ...... well as in CpG dinucleotides.
@en
type
label
Methylation-mediated deaminati ...... well as in CpG dinucleotides.
@en
prefLabel
Methylation-mediated deaminati ...... well as in CpG dinucleotides.
@en
P2093
P2860
P1433
P1476
Methylation-mediated deaminati ...... well as in CpG dinucleotides.
@en
P2093
Edward V Ball
Matthew Mort
Nadia A Chuzhanova
Peter D Stenson
P2860
P2888
P304
P356
10.1186/1479-7364-4-6-406
P577
2010-08-01T00:00:00Z
P5875
P6179
1050410787