First Detection of TR34 L98H and TR46 Y121F T289A Cyp51 Mutations in Aspergillus fumigatus Isolates in the United States. - Wikidata - awgldk - TriplyDB

First Detection of TR34 L98H and TR46 Y121F T289A Cyp51 Mutations in Aspergillus fumigatus Isolates in the United States.

First Detection of TR34 L98H and TR46 Y121F T289A Cyp51 Mutations in Aspergillus fumigatus Isolates in the United States.

http://www.wikidata.org/entity/Q41842226

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Emerging Threats in Antifungal-Resistant Fungal Pathogens Epidemiological and Genomic Landscape of Azole Resistance Mechanisms in Aspergillus Fungi A Novel Zn2-Cys6 Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions Triazole Resistance in Aspergillus Species: An Emerging Problem.Clinical implications of globally emerging azole resistance in Aspergillus fumigatus.A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence.Quantitative Analysis of Single-Nucleotide Polymorphism for Rapid Detection of TR34/L98H- and TR46/Y121F/T289A-Positive Aspergillus fumigatus Isolates Obtained from Patients in Iran from 2010 to 2014.Epidemiology and Molecular Characterizations of Azole Resistance in Clinical and Environmental Aspergillus fumigatus Isolates from China.Regulation of Sterol Biosynthesis in the Human Fungal Pathogen Aspergillus fumigatus: Opportunities for Therapeutic Development Azole-resistant Aspergillus fumigatus harboring TR34/L98H, TR46/Y121F/T289A and TR53 mutations related to flower fields in Colombia.Emerging aspergillosis by azole-resistant Aspergillus fumigatus at an intensive care unit in the Netherlands, 2010 to 2013.Evaluation of MIC Strip Isavuconazole Test for Susceptibility Testing of Wild-Type and Non-Wild-Type Aspergillus fumigatus Isolates.Azole-Resistant Aspergillosis: Epidemiology, Molecular Mechanisms, and Treatment.The Role of In Vitro Susceptibility Testing in the Management of Candida and Aspergillus.Animal Models for Studying Triazole Resistance in Aspergillus fumigatus.Azole-resistant Aspergillus fumigatus in sawmills of Eastern France.In Vivo Efficacy of Liposomal Amphotericin B against Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates in Two Different Immunosuppression Models of Invasive Aspergillosis.Inter-country transfer of triazole-resistant Aspergillus fumigatus on plant bulbs.Reply to "Are the TR46/Y121F/T289A Mutations in Azole-Resistant Aspergillosis Patient Acquired or Environmental?"Simulations of CYP51A from Aspergillus fumigatus in a model bilayer provide insights into triazole drug resistance.Sensitisation of an Azole-Resistant Aspergillus fumigatus Strain containing the Cyp51A-Related Mutation by Deleting the SrbA Gene.Antifungal Susceptibility Testing Practices at Acute Care Hospitals Enrolled in the National Healthcare Safety Network, United States, 2011-2015.In vivo veritas: Aspergillus fumigatus proliferation and pathogenesis--conditionally speaking.Are the TR46/Y121F/T289A Mutations in Azole-Resistant Aspergillosis Patient Acquired or Environmental?Fungal-specific Cyp51 inhibitor VT-1598 demonstrates in vitro activity against Candida and Cryptococcus species, endemic fungi, including Coccidioides species, Aspergillus species and Rhizopus arrhizus.Molecular Tools for the Detection and Deduction of Azole Antifungal Drug Resistance Phenotypes in Aspergillus Species.A Simple and Universal System for Gene Manipulation in Aspergillus fumigatus: In Vitro-Assembled Cas9-Guide RNA Ribonucleoproteins Coupled with Microhomology Repair Templates.Triazole Resistance in Aspergillus spp.: A Worldwide Problem?Recognition of Azole-Resistant Aspergillosis by Physicians Specializing in Infectious Diseases, United States.Invasive Fungal Infections in Patients with Hematological Malignancies: Emergence of Resistant Pathogens and New Antifungal Therapies.Detection of TR34/L98H Cyp51A mutation through passive surveillance for azole-resistant Aspergillus fumigatus in the US, 2015-2017.Posaconazole MIC distributions for Aspergillus fumigatus SC by four methods: Impact of Cyp51A mutations on estimation of epidemiological cutoff values (ECVs/ECOFFs).Evolution of cross-resistance to medical triazoles in Aspergillus fumigatus through selection pressure of environmental fungicides.Isolation of azole-resistant Aspergillus fumigatus from the environment in the south-eastern USA.Hot topics in antifungal susceptibility testing: A new drug, a bad bug, sweeping caspofungin testing under the rug, and solving the ECV shrug.Itraconazole, Voriconazole, and Posaconazole CLSI MIC Distributions for Wild-Type and Azole-Resistant Isolates Multidrug-Resistant Aspergillus fumigatus Carrying Mutations Linked to Environmental Fungicide Exposure - Three States, 2010-2017

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P2860

First Detection of TR34 L98H and TR46 Y121F T289A Cyp51 Mutations in Aspergillus fumigatus Isolates in the United States.

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First Detection of TR34 L98H a ...... Isolates in the United States.

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Annette W Fothergill

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Carmita Sanders

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Deanna A Sutton

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Dora I McCarthy

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Felipe Gutierrez

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Hongxin Fan

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Jonathan R Lindner

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Veronica Garcia Gil

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P2860

Global burden of chronic pulmonary aspergillosis complicating sarcoidosis

Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults

Underlying conditions in chronic pulmonary aspergillosis including simple aspergilloma

Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism

Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence.

Factors associated with mortality in transplant patients with invasive aspergillosis

Identification of two different 14-alpha sterol demethylase-related genes (cyp51A and cyp51B) in Aspergillus fumigatus and other Aspergillus species.

First detection of TR46/Y121F/T289A and TR34/L98H alterations in Aspergillus fumigatus isolates from azole-naive patients in Denmark despite negative findings in the environment.

Passive surveillance for azole-resistant Aspergillus fumigatus, United States, 2011-2013

Clonal expansion and emergence of environmental multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR₃₄/L98H mutations in the cyp51A gene in India.

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10.1128/JCM.02478-15

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1

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Nathan P. Wiederhold

Mohammad T Albataineh

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2015-10-21T00:00:00Z

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26491179

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Aspergillus fumigatus

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