about
Messages do diffuse faster than messengers: reconciling disparate estimates of the morphogen bicoid diffusion coefficientYeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates.Modulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxiaSingle-cell quantification of molecules and rates using open-source microscope-based cytometry.Using Cell-ID 1.4 with R for microscope-based cytometryThe Alpha Project: a model system for systems biology research.Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.Utilization of extracellular information before ligand-receptor binding reaches equilibrium expands and shifts the input dynamic range.Regulated cell-to-cell variation in a cell-fate decision system.Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range.Nonlinear mixed-effects modelling for single cell estimation: when, why, and how to use itQuantitative measurement of protein relocalization in live cells.Negative feedback that improves information transmission in yeast signallingYeast GPCR signaling reflects the fraction of occupied receptors, not the numberTransforming growth factor beta1 regulates follistatin mRNA expression during in vitro bovine granulosa cell differentiation.Impact of upstream and downstream constraints on a signaling module's ultrasensitivity.Modification of Akt by SUMO conjugation regulates alternative splicing and cell cycle.Pheromone-induced morphogenesis improves osmoadaptation capacity by activating the HOG MAPK pathway.Compartmentalization of a bistable switch enables memory to cross a feedback-driven transition.Modelling reveals novel roles of two parallel signalling pathways and homeostatic feedbacks in yeast.Expression of 3 beta-hydroxysteroid dehydrogenase in early bovine embryo development.Regulation of metalloproteinases by nitric oxide in human trophoblast cells in culture.Push-Pull and Feedback Mechanisms Can Align Signaling System Outputs with Inputs.In vivo evidences of early neurosteroid synthesis in the developing rat central nervous system and placenta.CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5.Single-cell profiling screen identifies microtubule-dependent reduction of variability in signaling.Using Cell-ID 1.4 with R for microscope-based cytometry.Heat-stress triggers MAPK crosstalk to turn on the hyperosmotic response pathwayOptical techniques provide information on various effective diffusion coefficients in the presence of trapsNitric oxide induces gelatinase A (matrix metalloproteinase 2) during rat embryo implantationMitotic and pheromone-specific intrinsic polarization cues interfere with gradient sensing in Saccharomyces cerevisiae
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Alejandro Colman-Lerner
@ast
Alejandro Colman-Lerner
@en
Alejandro Colman-Lerner
@es
type
label
Alejandro Colman-Lerner
@ast
Alejandro Colman-Lerner
@en
Alejandro Colman-Lerner
@es
prefLabel
Alejandro Colman-Lerner
@ast
Alejandro Colman-Lerner
@en
Alejandro Colman-Lerner
@es
P106
P1153
6602680891
P21
P31
P496
0000-0002-2557-8883