Optimization of the HA-1-specific T-cell receptor for gene therapy of hematologic malignancies. - Wikidata - awgldk - TriplyDB

Optimization of the HA-1-specific T-cell receptor for gene therapy of hematologic malignancies.

Optimization of the HA-1-specific T-cell receptor for gene therapy of hematologic malignancies.

http://www.wikidata.org/entity/Q41851295

about

Adoptive T-cell therapy for Leukemia Extracellular domains of CD8α and CD8ß subunits are sufficient for HLA class I restricted helper functions of TCR-engineered CD4(+) T cells.Augmentation of anti-tumor immunity by adoptive T-cell transfer after allogeneic hematopoietic stem cell transplantation.Challenges in T cell receptor gene therapy.The expanding horizon of immunotherapy in the treatment of malignant disorders: allogeneic hematopoietic stem cell transplantation and beyond.A Good Manufacturing Practice procedure to engineer donor virus-specific T cells into potent anti-leukemic effector cells.Minor histocompatibility Ags: identification strategies, clinical results and translational perspectives.Strategies for improving the efficacy of donor lymphocyte infusion following stem cell transplantation.Optimizing T-cell receptor gene therapy for hematologic malignancies.Generation and administration of HA-1-specific T-cell lines for the treatment of patients with relapsed leukemia after allogeneic stem cell transplantation: a pilot study.Targeting Leukemia Stem Cells in the Bone Marrow Niche.

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Optimization of the HA-1-specific T-cell receptor for gene therapy of hematologic malignancies.

http://www.wikidata.org/entity/Q41851295

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Optimization of the HA-1-speci ...... y of hematologic malignancies.

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type

label

Optimization of the HA-1-speci ...... y of hematologic malignancies.

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Optimization of the HA-1-speci ...... y of hematologic malignancies.

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HAEMATOL.2010.025916

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Optimization of the HA-1-speci ...... y of hematologic malignancies.

@en

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Esther H M van Egmond

http://www.w3.org/2001/XMLSchema#string

J H Frederik Falkenburg

http://www.w3.org/2001/XMLSchema#string

Marleen M van Loenen

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Mirjam H M Heemskerk

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Renate S Hagedoorn

http://www.w3.org/2001/XMLSchema#string

Renate de Boer

http://www.w3.org/2001/XMLSchema#string

P2860

Mixed T cell receptor dimers harbor potentially harmful neoreactivity.

Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemia

Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application.

Facilitating matched pairing and expression of TCR chains introduced into human T cells.

Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations

Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.

Codon modification of T cell receptors allows enhanced functional expression in transgenic human T cells.

Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer.

Peptide-MHC class I tetrameric complexes display exquisite ligand specificity.

Interindividual conservation of T-cell receptor beta chain variable regions by minor histocompatibility antigen-specific HLA-A*0201-restricted cytotoxic T-cell clones.

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477-481

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10.3324/HAEMATOL.2010.025916

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3

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96

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2010-11-25T00:00:00Z

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49637736

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21109688

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3046283

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