Cleavage of amyloid beta peptide during constitutive processing of its precursor.
about
A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer diseaseImplications of the serine protease HtrA1 in amyloid precursor protein processingLysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin SA metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.P3 beta-amyloid peptide has a unique and potentially pathogenic immunohistochemical profile in Alzheimer's disease brainSynaptic plasticity in animal models of early Alzheimer's diseaseValsartan lowers brain beta-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer diseaseBACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor proteinPossible involvement of copper(II) in Alzheimer disease.The Beta-amyloid protein of Alzheimer's disease: communication breakdown by modifying the neuronal cytoskeletonPlatelets and Alzheimer's disease: Potential of APP as a biomarkerGeneral anesthetics and β-amyloid proteinStructure of Alzheimer's disease amyloid precursor protein copper-binding domain at atomic resolutionStructural Correlates of Antibodies Associated with Acute Reversal of Amyloid -related Behavioral Deficits in a Mouse Model of Alzheimer DiseaseStructural Basis for Matrix Metalloproteinase-2 (MMP-2)-selective Inhibitory Action of -Amyloid Precursor Protein-derived InhibitorAlzheimer's disease: Targeting the Cholinergic SystemPMEL Amyloid Fibril Formation: The Bright Steps of PigmentationCurrent and future implications of basic and translational research on amyloid-β peptide production and removal pathwaysRegulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding proteinConstitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloproteaseZyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brainProteolytic processing of Alzheimer's β-amyloid precursor proteinTrafficking and proteolytic processing of APPCargo trafficking in Alzheimer’s disease: the possible role of retromerEvidence for a membrane defect in Alzheimer disease brainIncreased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarkerBACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous systemThe catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid beta peptide: implications for Alzheimer disease pathogenesisStimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formationIdentification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursorSerotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretionCholesterol is an important factor affecting the membrane insertion of beta-amyloid peptide (A beta 1-40), which may potentially inhibit the fibril formation.Shedding of somatic angiotensin-converting enzyme (ACE) is inefficient compared with testis ACE despite cleavage at identical stalk sitesEffects of gamma-secretase inhibition on the amyloid beta isoform pattern in a mouse model of Alzheimer's disease.Generation of C-terminally truncated amyloid-beta peptides is dependent on gamma-secretase activity.Serine proteases in rodent hippocampus.Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10Nucleotide, cytogenetic and expression impact of the human chromosome 8p23.1 inversion polymorphism.The amyloid precursor protein of Alzheimer's disease and the Abeta peptide.
P2860
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P2860
Cleavage of amyloid beta peptide during constitutive processing of its precursor.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Cleavage of amyloid beta peptide during constitutive processing of its precursor.
@en
type
label
Cleavage of amyloid beta peptide during constitutive processing of its precursor.
@en
prefLabel
Cleavage of amyloid beta peptide during constitutive processing of its precursor.
@en
P2093
P356
P1433
P1476
Cleavage of amyloid beta peptide during constitutive processing of its precursor.
@en
P2093
Beattie EC
Blacher RW
Culwell AR
Oltersdorf T
P304
P356
10.1126/SCIENCE.2111583
P407
P577
1990-06-01T00:00:00Z