The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5.
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Tetrodotoxin-sensitive α-subunits of voltage-gated sodium channels are relevant for inhibition of cardiac sodium currents by local anesthetics.Inhibition of the cardiac Na⁺ channel α-subunit Nav1.5 by propofol and dexmedetomidine.Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.Determination of the unbound fraction of R- and S-methadone in human brain.
P2860
The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5.
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name
The opioid methadone induces a ...... cardiac Na⁺ channel, Na(v)1.5.
@en
type
label
The opioid methadone induces a ...... cardiac Na⁺ channel, Na(v)1.5.
@en
prefLabel
The opioid methadone induces a ...... cardiac Na⁺ channel, Na(v)1.5.
@en
P2093
P2860
P356
P1476
The opioid methadone induces a ...... cardiac Na⁺ channel, Na(v)1.5.
@en
P2093
A O O'Reilly
C Stoetzer
E Eberhardt
J de la Roche
P2860
P304
P356
10.1111/BPH.12465
P407
P577
2014-01-01T00:00:00Z