The murine goblet cell protein mCLCA3 is a zinc-dependent metalloprotease with autoproteolytic activity.
about
Novel Roles for Chloride Channels, Exchangers, and Regulators in Chronic Inflammatory Airway DiseasesIL-13-induced airway mucus production is attenuated by MAPK13 inhibition.CLCAs - a family of metalloproteases of intriguing phylogenetic distribution and with cases of substituted catalytic sites.Murine CLCA5 is uniquely expressed in distinct niches of airway epithelial cells.Loss of CLCA4 promotes epithelial-to-mesenchymal transition in breast cancer cellsThe Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice.Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype.Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteinsSecreted hCLCA1 is a signaling molecule that activates airway macrophages.rbCLCA1 is a putative metalloprotease family member: localization and catalytic domain identification.Impaired autoproteolytic cleavage of mCLCA6, a murine integral membrane protein expressed in enterocytes, leads to cleavage at the plasma membrane instead of the endoplasmic reticulum.Interspecies diversity of chloride channel regulators, calcium-activated 3 genes.Time for TMEM?Soluble mucus component CLCA1 modulates expression of leukotactic cytokines and BPIFA1 in murine alveolar macrophages but not in bone marrow-derived macrophages.Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity
P2860
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P2860
The murine goblet cell protein mCLCA3 is a zinc-dependent metalloprotease with autoproteolytic activity.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The murine goblet cell protein ...... with autoproteolytic activity.
@en
type
label
The murine goblet cell protein ...... with autoproteolytic activity.
@en
prefLabel
The murine goblet cell protein ...... with autoproteolytic activity.
@en
P2093
P2860
P1433
P1476
The murine goblet cell protein ...... with autoproteolytic activity.
@en
P2093
Achim D Gruber
Christoph Weise
Lars Mundhenk
Matthias Kaup
Melanie K Bothe
P2860
P2888
P304
P356
10.1007/S10059-011-0158-8
P577
2011-11-09T00:00:00Z