Polo-like kinase 1 inhibitors, mitotic stress and the tumor suppressor p53.

Polo-like kinase 1 inhibitors, mitotic stress and the tumor suppressor p53.

Item
http://www.wikidata.org/entity/Q41866750
Comprehensive genomic characterization of head and neck squamous cell carcinomasPhase I study of oral rigosertib (ON 01910.Na), a dual inhibitor of the PI3K and Plk1 pathways, in adult patients with advanced solid malignanciesAdenovirus replaces mitotic checkpoint controls.Loss of p21Cip1/CDKN1A renders cancer cells susceptible to Polo-like kinase 1 inhibitionB-cell lymphoma 6 promotes proliferation and survival of trophoblastic cellsAberrant DNA Double-strand Break Repair Threads in Breast Carcinoma: Orchestrating Genomic Insult Survival.Remote loading of preencapsulated drugs into stealth liposomes.Battle of the eternal rivals: restoring functional p53 and inhibiting Polo-like kinase 1 as cancer therapy.Current assessment of polo-like kinases as anti-tumor drug targets.Combining p53 stabilizers with metformin induces synergistic apoptosis through regulation of energy metabolism in castration-resistant prostate cancer.Spotlight on Volasertib: Preclinical and Clinical Evaluation of a Promising Plk1 Inhibitor.Functional analysis of phosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cellsp21Waf1/Cip1 deficiency causes multiple mitotic defects in tumor cells.Polo-like kinase 1 inhibition causes decreased proliferation by cell cycle arrest, leading to cell death in glioblastoma.The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation.Deficiency of RITA results in multiple mitotic defects by affecting microtubule dynamics.
P2860

Polo-like kinase 1 inhibitors, mitotic stress and the tumor suppressor p53.

Item
http://www.wikidata.org/entity/Q41866750
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Polo-like kinase 1 inhibitors, mitotic stress and the tumor suppressor p53.
@en
type
label
Polo-like kinase 1 inhibitors, mitotic stress and the tumor suppressor p53.
@en
prefLabel
Polo-like kinase 1 inhibitors, mitotic stress and the tumor suppressor p53.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Polo-like kinase 1 inhibitors, mitotic stress and the tumor suppressor p53.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932