The nonribosomal peptide synthetase enzyme DdaD tethers N(β)-fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-ketoglutarate-dependent epoxidation by DdaC during dapdiamide antibiotic biosynthesis.
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Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactoneComplexity generation during natural product biosynthesis using redox enzymesCharacterization of the biosynthetic operon for the antibacterial peptide herbicolin in Pantoea vagans biocontrol strain C9-1 and incidence in Pantoea species.Enzymatic strategies and biocatalysts for amide bond formation: tricks of the trade outside of the ribosome.Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid polyketide scaffolds.Assessment of the relevance of the antibiotic 2-amino-3-(oxirane-2,3-dicarboxamido)-propanoyl-valine from Pantoea agglomerans biological control strains against bacterial plant pathogens.Ribosome-independent biosynthesis of biologically active peptides: Application of synthetic biology to generate structural diversity.Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery.Electronic structure analysis of the oxygen-activation mechanism by Fe(II)- and α-ketoglutarate (αKG)-dependent dioxygenases.Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants.Biosynthesis of Oligopeptides Using ATP-Grasp Enzymes.The Pseudomonas aeruginosa antimetabolite L -2-amino-4-methoxy-trans-3-butenoic acid (AMB) is made from glutamate and two alanine residues via a thiotemplate-linked tripeptide precursor.Non-heme dioxygenase catalyzes atypical oxidations of 6,7-bicyclic systems to form the 6,6-quinolone core of viridicatin-type fungal alkaloids.A head-to-head comparison of eneamide and epoxyamide inhibitors of glucosamine-6-phosphate synthase from the dapdiamide biosynthetic pathway
P2860
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P2860
The nonribosomal peptide synthetase enzyme DdaD tethers N(β)-fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-ketoglutarate-dependent epoxidation by DdaC during dapdiamide antibiotic biosynthesis.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The nonribosomal peptide synth ...... amide antibiotic biosynthesis.
@en
type
label
The nonribosomal peptide synth ...... amide antibiotic biosynthesis.
@en
prefLabel
The nonribosomal peptide synth ...... amide antibiotic biosynthesis.
@en
P2093
P2860
P356
P1476
The nonribosomal peptide synth ...... iamide antibiotic biosynthesis
@en
P2093
Christopher T Walsh
J Martin Bollinger
Marie A Hollenhorst
Neil L Kelleher
Stefanie B Bumpus
P2860
P304
15773-15781
P356
10.1021/JA1072367
P407
P577
2010-11-01T00:00:00Z