A critical assessment of combined ligand- and structure-based approaches to HERG channel blocker modeling.
about
Novel inhibitors induce large conformational changes of GAB1 pleckstrin homology domain and kill breast cancer cellsModelling three-dimensional protein structures for applications in drug design.Novel Bayesian classification models for predicting compounds blocking hERG potassium channels.Tuning HERG out: antitarget QSAR models for drug developmentA novel multi-modal drug repurposing approach for identification of potent ACK1 inhibitorsIn silico prediction of hERG inhibition.A 2015 focus on preventing drug-induced arrhythmias.Assessing hERG pore models as templates for drug docking using published experimental constraints: the inactivated state in the context of drug block.Polypharmacology in Drug Development: A Minireview of Current Technologies.Development of Safe Drugs: The hERG Challenge.Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase InhibitorReplacing the thorough QT study: reflections of a baby in the bath water.Predictive QSAR models development and validation for human ether-a-go-go related gene (hERG) blockers using newer toolsExperimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities
P2860
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P2860
A critical assessment of combined ligand- and structure-based approaches to HERG channel blocker modeling.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
A critical assessment of combi ...... HERG channel blocker modeling.
@en
type
label
A critical assessment of combi ...... HERG channel blocker modeling.
@en
prefLabel
A critical assessment of combi ...... HERG channel blocker modeling.
@en
P2093
P2860
P356
P1476
A critical assessment of combi ...... HERG channel blocker modeling.
@en
P2093
Lei Du-Cuny
Shuxing Zhang
P2860
P304
P356
10.1021/CI200271D
P577
2011-10-13T00:00:00Z