Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment
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Defects of the Glycinergic Synapse in Zebrafish.Function Over Form: Modeling Groups of Inherited Neurological Conditions in ZebrafishAdvancing epilepsy genetics in the genomic eraZebrafish as an emerging model for studying complex brain disordersGenetic epilepsy syndromes without structural brain abnormalities: clinical features and experimental modelsAdvances on genetic rat models of epilepsy.Epileptic encephalopathies: new genes and new pathwaysPathogenesis and new candidate treatments for infantile spasms and early life epileptic encephalopathies: A view from preclinical studiesPharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramineA Novel Long-term, Multi-Channel and Non-invasive Electrophysiology Platform for Zebrafish.Drug screening: zebrafish as a tool for studying epileptic-related chemical compoundsMicroarray Noninvasive Neuronal Seizure Recordings from Intact Larval ZebrafishLeveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology.Prioritizing the development of mouse models for childhood brain disordersZebrafish behavioral profiling identifies multitarget antipsychotic-like compounds.Advancements in zebrafish applications for 21st century toxicology.Epilepsy, Behavioral Abnormalities, and Physiological Comorbidities in Syntaxin-Binding Protein 1 (STXBP1) Mutant Zebrafish.Searching for the ideal antiepileptogenic agent in experimental models: single treatment versus combinatorial treatment strategiesZebrafish models for translational neuroscience research: from tank to bedside.ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons.Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus.Screening of conventional anticonvulsants in a genetic mouse model of epilepsy.Optical mapping of neuronal activity during seizures in zebrafish.Zebrafish models in translational research: tipping the scales toward advancements in human health.SCN8A encephalopathy: Research progress and prospectsDiscovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish.15 years of zebrafish chemical screeningLarge-Scale Phenotype-Based Antiepileptic Drug Screening in a Zebrafish Model of Dravet Syndrome(1,2,3).Zebrafish needle EMG: a new tool for high-throughput drug screensClemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome.Chemical screening in zebrafish for novel biological and therapeutic discovery.A roadmap for precision medicine in the epilepsies.Analysis of Zebrafish Larvae Skeletal Muscle Integrity with Evans Blue Dye.Molecular subtyping and improved treatment of neurodevelopmental disease.Model systems for studying cellular mechanisms of SCN1A-related epilepsy.Genetic forms of epilepsies and other paroxysmal disorders2014 Epilepsy Benchmarks Area II: Prevent Epilepsy and Its Progression.2014 Epilepsy Benchmarks Area III: Improve Treatment Options for Controlling Seizures and Epilepsy-Related Conditions Without Side EffectsZebrafish Models of Prader-Willi Syndrome: Fast Track to Pharmacotherapeutics.Chemical suppression of defects in mitotic spindle assembly, redox control, and sterol biosynthesis by hydroxyurea.
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Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Drug screening in Scn1a zebraf ...... tial Dravet syndrome treatment
@en
type
label
Drug screening in Scn1a zebraf ...... tial Dravet syndrome treatment
@en
prefLabel
Drug screening in Scn1a zebraf ...... tial Dravet syndrome treatment
@en
P2860
P356
P1476
Drug screening in Scn1a zebraf ...... tial Dravet syndrome treatment
@en
P2093
Gabriela A Hortopan
P2860
P2888
P356
10.1038/NCOMMS3410
P407
P577
2013-01-01T00:00:00Z