Conditional disruption of mouse Klf5 results in defective eyelids with malformed meibomian glands, abnormal cornea and loss of conjunctival goblet cells.
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The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformationKLF5 inhibits angiogenesis in PTEN-deficient prostate cancer by attenuating AKT activation and subsequent HIF1α accumulationThe Histone Methyltransferase Gene Absent, Small, or Homeotic Discs-1 Like Is Required for Normal Hox Gene Expression and Fertility in MiceFGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glandsKruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epitheliumDevelopment of novel filtering criteria to analyze RNA-sequencing data obtained from the murine ocular lens during embryogenesisLoss of Sip1 leads to migration defects and retention of ectodermal markers during lens development.Critical role of Klf5 in regulating gene expression during post-eyelid opening maturation of mouse corneas.Tear film mucins: front line defenders of the ocular surface; comparison with airway and gastrointestinal tract mucinsKlf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathwaysTGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium.Regulation of anti-apoptotic signaling by Kruppel-like factors 4 and 5 mediates lapatinib resistance in breast cancer.Hemizygous Le-Cre transgenic mice have severe eye abnormalities on some genetic backgrounds in the absence of LoxP sitesKruppel-like factor 5 (KLF5) is critical for conferring uterine receptivity to implantation.Spatiotemporally Regulated Ablation of Klf4 in Adult Mouse Corneal Epithelial Cells Results in Altered Epithelial Cell Identity and Disrupted Homeostasis.Mastermind-like transcriptional co-activator-mediated Notch signaling is indispensable for maintaining conjunctival epithelial identity.Requirement of fatty acid transport protein 4 for development, maturation, and function of sebaceous glands in a mouse model of ichthyosis prematurity syndrome.Spdef null mice lack conjunctival goblet cells and provide a model of dry eye.Krüppel-like factor 5 is essential for maintenance of barrier function in mouse colon.Kruppel-like Pluripotency Factors as Modulators of Cancer Cell Therapeutic Responses.Goblet cells of the conjunctiva: A review of recent findingsGenetically modified laboratory mice with sebaceous glands abnormalities.Lacrimal gland development: From signaling interactions to regenerative medicine.Proteolytic activity in the meibomian gland: Implications to health and disease.Spatiotemporally Controlled Ablation of Klf5 Results in Dysregulated Epithelial Homeostasis in Adult Mouse Corneas.Ocular surface development and gene expression.The core planar cell polarity gene, Vangl2, maintains apical-basal organisation of the corneal epithelium.Meibomian gland morphogenesis requires developmental eyelid closure and lid fusion.Regulation of mouse lens maturation and gene expression by Krüppel-like factor 4Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition.
P2860
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P2860
Conditional disruption of mouse Klf5 results in defective eyelids with malformed meibomian glands, abnormal cornea and loss of conjunctival goblet cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Conditional disruption of mous ...... of conjunctival goblet cells.
@en
type
label
Conditional disruption of mous ...... of conjunctival goblet cells.
@en
prefLabel
Conditional disruption of mous ...... of conjunctival goblet cells.
@en
P2093
P2860
P1476
Conditional disruption of mous ...... of conjunctival goblet cells.
@en
P2093
Divya Gupta
Doreswamy Kenchegowda
Huajing Wan
Jeffrey Whitsett
Shivalingappa K Swamynathan
Sudha Swamynathan
P2860
P356
10.1016/J.YDBIO.2011.05.005
P407
P577
2011-05-11T00:00:00Z