Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis
about
Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)Therapeutic Targeting of TelomeraseOxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegenerationTelomere shortening in neurological disorders: an abundance of unanswered questions.Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells.Cytoplasmic TERT Associates to RNA Granules in Fully Mature Neurons: Role in the Translational Control of the Cell Cycle Inhibitor p15INK4BThe role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro.The Human Microcirculation: Regulation of Flow and BeyondCritical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation.Telomere shortening leads to earlier age of onset in ALS miceTelomerase activity in the various regions of mouse brain: non-radioactive telomerase repeat amplification protocol (TRAP) assayTelomerase Activity is Downregulated Early During Human Brain Development.Telomerase at the intersection of cancer and aging.Potential of telomerase activation in extending health span and longevity.Telomerase and mTOR in the brain: the mitochondria connection.Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease.Excitotoxic and Radiation Stress Increase TERT Levels in the Mitochondria and Cytosol of Cerebellar Purkinje Neurons.Expression of functional alternative telomerase RNA component gene in mouse brain and in motor neurons cells protects from oxidative stress.Differential decrease in soluble and DNA-bound telomerase in senescent human fibroblasts.Telomerase expression in amyotrophic lateral sclerosis (ALS) patients.The Emerging Roles for Telomerase in the Central Nervous System.
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P2860
Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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2012年论文
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2012年论文
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name
Novel telomerase-increasing co ...... amyotrophic lateral sclerosis
@en
type
label
Novel telomerase-increasing co ...... amyotrophic lateral sclerosis
@en
prefLabel
Novel telomerase-increasing co ...... amyotrophic lateral sclerosis
@en
P2093
P2860
P356
P1476
Novel telomerase-increasing co ...... amyotrophic lateral sclerosis
@en
P2093
Ailon Tichon
Aviv Gazit
Erez Eitan
Esther Priel
Shimon Slavin
P2860
P304
P356
10.1002/EMMM.201200212
P577
2012-02-20T00:00:00Z