Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions
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The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer.Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism.One-step enzymatic modification of the cell surface redirects cellular cytotoxicity and parasite tropism.Porphyromonas gingivalis Type IX Secretion Substrates Are Cleaved and Modified by a Sortase-Like MechanismA Modular Vaccine Development Platform Based on Sortase-Mediated Site-Specific Tagging of Antigens onto Virus-Like ParticlesBioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids.GPR107, a G-protein-coupled receptor essential for intoxication by Pseudomonas aeruginosa exotoxin A, localizes to the Golgi and is cleaved by furinBispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activityProtocol for sortase-mediated construction of DNA-protein hybrids and functional nanostructures.Site-specific chemoenzymatic labeling of aerolysin enables the identification of new aerolysin receptorsIntra-spike crosslinking overcomes antibody evasion by HIV-1Noninvasive imaging of immune responses.Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.Type VI secretion system sheaths as nanoparticles for antigen display.A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assemblyCrystal structure of a substrate-engaged SecY protein-translocation channelImproved variants of SrtA for site-specific conjugation on antibodies and proteins with high efficiencyPhenotypic lentivirus screens to identify functional single domain antibodiesRecent advances in sortase-catalyzed ligation methodology.Molecular basis of outer kinetochore assembly on CENP-T.Sortagging: a robust and efficient chemoenzymatic ligation strategy.Site-specific protein modification using immobilized sortase in batch and continuous-flow systems.Production of unnaturally linked chimeric proteins using a combination of sortase-catalyzed transpeptidation and click chemistry.Rapid and Direct VHH and Target Identification by Staphylococcal Surface Display LibrariesStructurally Defined αMHC-II Nanobody-Drug Conjugates: A Therapeutic and Imaging System for B-Cell Lymphoma.The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment.Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology.Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.Noninvasive Imaging of Human Immune Responses in a Human Xenograft Model of Graft-Versus-Host Disease.Host cell binding of the flagellar tip protein of Campylobacter jejuni.Generation of Immunity against Pathogens via Single-Domain Antibody-Antigen Constructs.Inhibitory effects of antibiofilm compound 1 against Staphylococcus aureus biofilms.Fluorophore-Conjugated Holliday Junctions for Generating Super-Bright Antibodies and Antibody Fragments.Capture and Recycling of Sortase A through Site-Specific Labeling with Lithocholic Acid.Engineering peptide ligase specificity by proteomic identification of ligation sites.Synthesis of a Bifunctional Peptide Inhibitor-IgG1 Fc Fusion That Suppresses Experimental Autoimmune Encephalomyelitis.Targeting the N terminus for site-selective protein modification.Peptibodies: An elegant solution for a long-standing problem.A molecular engineering toolbox for the structural biologist.Orthogonal enzymatic reactions for rapid crosslinking and dynamic tuning of PEG-peptide hydrogels.
P2860
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P2860
Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Site-specific C-terminal and i ...... ing sortase-mediated reactions
@en
type
label
Site-specific C-terminal and i ...... ing sortase-mediated reactions
@en
prefLabel
Site-specific C-terminal and i ...... ing sortase-mediated reactions
@en
P2093
P2860
P356
P1433
P1476
Site-specific C-terminal and i ...... ing sortase-mediated reactions
@en
P2093
Annet E M Blom
Carla P Guimaraes
Christopher S Theile
Hidde L Ploegh
Lenka Kundrat
Martin D Witte
P2860
P2888
P304
P356
10.1038/NPROT.2013.101
P577
2013-08-29T00:00:00Z