BIM-mediated membrane insertion of the BAK pore domain is an essential requirement for apoptosis.
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Regulation of Bim in Health and DiseasePro-apoptotic Bax molecules densely populate the edges of membrane pores.Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membraneAdenovirus-delivered PDCD5 counteracts adriamycin resistance of osteosarcoma cells through enhancing apoptosis and inhibiting Pgp.The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM)MCL-1-independent mechanisms of synergy between dual PI3K/mTOR and BCL-2 inhibition in diffuse large B cell lymphoma.Low dose of lenalidmide and PI3K/mTOR inhibitor trigger synergistic cytoxicity in activated B cell-like subtype of diffuse large B cell lymphoma.Cellular responses to HSV-1 infection are linked to specific types of alterations in the host transcriptome.Knockdown of miR-221 promotes the cisplatin-inducing apoptosis by targeting the BIM-Bax/Bak axis in breast cancer.Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment.Mcl-1 is vital for neutrophil survival.Dissociation of Bak α1 helix from the core and latch domains is required for apoptosis.Disordered clusters of Bak dimers rupture mitochondria during apoptosis.Apoptotic foci at mitochondria: in and around Bax pores.Pore formation by dimeric Bak and Bax: an unusual pore?MiR-24-BIM-Smac/DIABLO axis controls the sensitivity to doxorubicin treatment in osteosarcoma.UMI-77 primes glioma cells for TRAIL-induced apoptosis by unsequestering Bim and Bak from Mcl-1.Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis
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P2860
BIM-mediated membrane insertion of the BAK pore domain is an essential requirement for apoptosis.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
BIM-mediated membrane insertio ...... ial requirement for apoptosis.
@en
type
label
BIM-mediated membrane insertio ...... ial requirement for apoptosis.
@en
prefLabel
BIM-mediated membrane insertio ...... ial requirement for apoptosis.
@en
P2860
P1433
P1476
BIM-mediated membrane insertio ...... ial requirement for apoptosis.
@en
P2093
Gerald M Cohen
Nicholas Harper
P2860
P304
P356
10.1016/J.CELREP.2013.09.010
P577
2013-10-10T00:00:00Z