5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2.

about

Reviving the guardian of the genome: Small molecule activators of p53.Tyrosyl-DNA phosphodiesterases: rescuing the genome from the risks of relaxation.6-(Ar)Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84).

P2860

Q39205536-A14BE1BC-5846-41DD-983F-A32E5FBCB6EC Q46431649-D1B02C83-0AE5-4C19-8DFA-D0E397148123 Q55692244-C0C6BE88-8946-4F4F-A274-8971093A10C1

P2860

5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2.

Item

http://www.wikidata.org/entity/Q41885302

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2.

@en

type

Item

label

5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2.

@en

prefLabel

5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2.

@en

P1476

5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2

@en

P2093

Andreas Hock

http://www.w3.org/2001/XMLSchema#string

Karen H Vousden

http://www.w3.org/2001/XMLSchema#string

Michael P Dickens

http://www.w3.org/2001/XMLSchema#string

Mokdad Mezna

http://www.w3.org/2001/XMLSchema#string

Patricia Roxburgh

http://www.w3.org/2001/XMLSchema#string

P2860

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

An essential function of the extreme C-terminus of MDM2 can be provided by MDMX

Molecular basis for the inhibition of p53 by Mdmx

Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans

Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

Regulation of p53 stability by Mdm2

Themes and variations on ubiquitylation

Synthesis of 5-deazaflavin derivatives and their activation of p53 in cells

p53 in health and disease

Small-molecule inhibitors of MDM2 as new anticancer therapeutics.

P304

6868-6877

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.BMC.2013.09.038

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Peter M. Fischer

Barrie Kellam

P577

2013-09-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

257647190

http://www.w3.org/2001/XMLSchema#string

P698

24113239

http://www.w3.org/2001/XMLSchema#string

P921

protein ubiquitination

P932

3898830

http://www.w3.org/2001/XMLSchema#string

5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2.

about

P2860

P2860

5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P921

P932