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The X-ray crystal structure of an Arthrobacter protophormiae endo-beta-N-acetylglucosaminidase reveals a (beta/alpha)(8) catalytic domain, two ancillary domains and active site residues key for transglycosylation activityInhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysisThe conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway.Unique N-glycan moieties of the 66-kDa cell wall glycoprotein from the red microalga Porphyridium sp.Convergent chemoenzymatic synthesis of a library of glycosylated analogues of pramlintide: structure-activity relationships for amylin receptor agonism.Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.The role of the Maillard reaction in the formation of flavour compounds in dairy products--not only a deleterious reaction but also a rich source of flavour compounds.Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells.A surface plasmon resonance assay for measurement of neuraminidase inhibition, sensitivity of wild-type influenza neuraminidase and its H274Y mutant to the antiviral drugs zanamivir and oseltamivir.Development of a surface plasmon resonance assay to measure the binding affinity of wild-type influenza neuraminidase and its H274Y mutant to the antiviral drug zanamivir.Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of N-acetylmannosamine-6-phosphate 2-epimerase from methicillin-resistant Staphylococcus aureusThe ENGases: versatile biocatalysts for the production of homogeneous N-linked glycopeptides and glycoproteins.Streptococcus pneumoniae endohexosaminidase D; feasibility of using N-glycan oxazoline donors for synthetic glycosylation of a GlcNAc-asparagine acceptor.Gold Nanoparticles Decorated with Sialic Acid Terminated Bi-antennary N-Glycans for the Detection of Influenza Virus at Nanomolar Concentrations.Selective anomeric acetylation of unprotected sugars in water.2,3,4,6-Tetra-O-benzoyl-4-nitro-phenyl-1-thio-α-d-mannopyran-oside-dichloro-methane-diethyl ether mixed solvate (1/0.53/0.38).Gold Nanoparticles Decorated with Sialic Acid Terminated Bi-antennary N-Glycans for the Detection of Influenza Virus at Nanomolar Concentrations.Virtual Issue: Carbohydrates in the 21(st) Century: Synthesis and Applications.4-Methoxy-phenyl 2,3,4,6-tetra-O-acetyl-1-thio-α-d-mannopyran-oside.Solvent interactions and conformational choice in a core N-glycan segment: gas phase conformation of the central, branching trimannose unit and its singly hydrated complex.Lectin-directed enzyme activated prodrug therapy (LEAPT): Synthesis and evaluation of rhamnose-capped prodrugs.Glycosylation catalyzed by a chiral Brønsted acid.Endohexosaminidase-catalysed glycosylation with oxazoline donors: effects of organic co-solvent and pH on reactions catalysed by Endo A and Endo M.Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.Glycosylation of pramlintide: synthetic glycopeptides that display in vitro and in vivo activities as amylin receptor agonists.Stereoselective 1,2-cis glycosylation of 2-O-allyl protected thioglycosides.Ready protease-catalyzed synthesis of carbohydrate-amino acid conjugates.Synthesis of fluorescence-labelled disaccharide substrates of glucosidase II.Selective activation of glycosyl donors utilising electrochemical techniques: a study of the thermodynamic oxidation potentials of a range of chalcoglycosides.Selective electrochemical glycosylation by reactivity tuning.Synthesis of glucose derivatives modified at the 4-OH as potential chain-terminators of cellulose biosynthesis; herbicidal activity of simple monosaccharide derivatives.Probing replacement of pyrophosphate via click chemistry; synthesis of UDP-sugar analogues as potential glycosyl transferase inhibitors.Synthesis of Arabino glycosyl triazoles as potential inhibitors of mycobacterial cell wall biosynthesis.Endohexosaminidase-catalysed glycosylation with oxazoline donors: fine tuning of catalytic efficiency and reversibility.Chemical site-selective prenylation of proteins.Synthesis of UDP-glucose derivatives modified at the 3-OH as potential chain terminators of beta-glucan biosynthesis.Voltammetric and electrochemical ESR studies of oxidation reactions mediated by tris(4-bromophenyl)amine in acetonitrile.Synthesis of the Glc3Man N-glycan tetrasaccharide by iterative allyl IAD.Size-optimized galactose-capped gold nanoparticles for the colorimetric detection of heat-labile enterotoxin at nanomolar concentrations.A double-click approach to the protecting group free synthesis of glycoconjugates.
P50
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P50
description
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researcher
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հետազոտող
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name
Antony J. Fairbanks
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Antony J. Fairbanks
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Antony J. Fairbanks
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Antony J. Fairbanks
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type
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Antony J. Fairbanks
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Antony J. Fairbanks
@en
Antony J. Fairbanks
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Antony J. Fairbanks
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prefLabel
Antony J. Fairbanks
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Antony J. Fairbanks
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Antony J. Fairbanks
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Antony J. Fairbanks
@nl
P106
P1153
7004896482
P21
P31
P496
0000-0002-9975-3269