The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1.
about
LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migrationComputer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeletonMutations in an Atypical TIR-NB-LRR-LIM Resistance Protein Confer Autoimmunity.Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and subsequent lamellipod extension.Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis.LIM kinases: cofilin and beyond.Stromal cell-derived factor 1alpha activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis.CD29 integrin- and LIMK1/cofilin-mediated actin reorganization regulates the migration of haematopoietic progenitor cells underneath bone marrow stromal cells.Caspase-mediated cleavage and activation of LIM-kinase 1 and its role in apoptotic membrane blebbing.Inhibition of nuclear import of LIMK2 in endothelial cells by protein kinase C-dependent phosphorylation at Ser-283.
P2860
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P2860
The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1.
@en
type
label
The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1.
@en
prefLabel
The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1.
@en
P2093
P2860
P1433
P1476
The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1
@en
P2093
P2860
P304
P356
10.1042/0264-6021:3430099
10.1042/BJ3430099
P407
P478
P577
1999-10-01T00:00:00Z