The molecular basis for species-specific activation of human TRPA1 protein by protons involves poorly conserved residues within transmembrane domains 5 and 6.
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TRPA1 as a drug target--promise and challengesNociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain PathologiesDifferential Activation of TRP Channels in the Adult Rat Spinal Substantia Gelatinosa by Stereoisomers of Plant-Derived ChemicalsSensitization of TRPA1 by Protein Kinase AEugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses.Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation.Human sensory neurons: Membrane properties and sensitization by inflammatory mediatorsMolecular basis determining inhibition/activation of nociceptive receptor TRPA1 protein: a single amino acid dictates species-specific actions of the most potent mammalian TRPA1 antagonist.Polysulfide evokes acute pain through the activation of nociceptive TRPA1 in mouse sensory neurons.TRPs in taste and chemesthesis.Selective Activation of Nociceptor TRPV1 Channel and Reversal of Inflammatory Pain in Mice by a Novel Coumarin Derivative Muralatin L from Murraya alataA painful TR(i)P to lysosomes.Sensory TRP channels: the key transducers of nociception and pain.Identification of a putative binding site critical for general anesthetic activation of TRPA1.Assessments of sensory plasticity after spinal cord injury across species.Lactate is a potent inhibitor of the capsaicin receptor TRPV1.TMC-1 Mediates Alkaline Sensation in C. elegans through Nociceptive Neurons.A vicious cycle between acid sensing and survival signaling in myeloma cells: acid-induced epigenetic alterationTRPA1 and TRPV1 are required for lidocaine-evoked calcium influx and neuropeptide release but not cytotoxicity in mouse sensory neurons.TRPA1 channels: molecular sentinels of cellular stress and tissue damage.Agonist-induced sensitisation of the irritant receptor ion channel TRPA1.Regulation of Pain and Itch by TRP Channels.Propacetamol-Induced Injection Pain Is Associated with Activation of Transient Receptor Potential Vanilloid 1 Channels.Hypotonicity-induced cell swelling activates TRPA1.Transient Receptor Potential Channel A1 (TRPA1) Regulates Sulfur Mustard-Induced Expression of Heat Shock 70 kDa Protein 6 () In Vitro
P2860
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P2860
The molecular basis for species-specific activation of human TRPA1 protein by protons involves poorly conserved residues within transmembrane domains 5 and 6.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The molecular basis for specie ...... transmembrane domains 5 and 6.
@en
type
label
The molecular basis for specie ...... transmembrane domains 5 and 6.
@en
prefLabel
The molecular basis for specie ...... transmembrane domains 5 and 6.
@en
P2093
P2860
P356
P1476
The molecular basis for specie ...... transmembrane domains 5 and 6.
@en
P2093
Alexandra B Klinger
Andreas Leffler
Florian Wegner
Jeanne de la Roche
Michael J M Fischer
Mirjam J Eberhardt
Nancy Stanslowsky
Wolfgang Koppert
P2860
P304
20280-20292
P356
10.1074/JBC.M113.479337
P407
P577
2013-05-24T00:00:00Z