Effects of ammonia on CHO cell growth, erythropoietin production, and glycosylation.
about
Overcoming nutrient limitations for cell-based production of influenza vaccine.Fermentanomics: Relating quality attributes of a monoclonal antibody to cell culture process variables and raw materials using multivariate data analysis.Glycosylation-related genes in NS0 cells are insensitive to moderately elevated ammonium concentrationsImpact of cultivation conditions on N-glycosylation of influenza virus a hemagglutinin produced in MDCK cell culture.5-thiomannosides block the biosynthesis of dolichol-linked oligosaccharides and mimic class I congenital disorders of glycosylationRelated effects of cell adaptation to serum-free conditions on murine EPO production and glycosylation by CHO cellsCaspase activation, sialidase release and changes in sialylation pattern of recombinant human erythropoietin produced by CHO cells in batch and fed-batch cultures.GDP-mannose pyrophosphorylase is a genetic determinant of ammonium sensitivity in Arabidopsis thaliana.The effects of culture conditions on the glycosylation of secreted human placental alkaline phosphatase produced in Chinese hamster ovary cells.Optimisation of the cellular metabolism of glycosylation for recombinant proteins produced by Mammalian cell systems.Using cell engineering and omic tools for the improvement of cell culture processes.Towards dynamic metabolic flux analysis in CHO cell cultures.CHO cells in biotechnology for production of recombinant proteins: current state and further potential.Current state and perspectives on erythropoietin production.Gel electrophoretic methods for the analysis of biosimilar pharmaceuticals using the example of recombinant erythropoietin.Glycosylation: impact, control and improvement during therapeutic protein production.Post-translational structural modifications of immunoglobulin G and their effect on biological activity.Selection of chemically defined media for CHO cell fed-batch culture processes.A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.Adaptation of CHO cells in serum-free conditions for erythropoietin production: Application of EVOP technique for process optimization.Modulation and modeling of monoclonal antibody N-linked glycosylation in mammalian cell perfusion reactors.What can mathematical modelling say about CHO metabolism and protein glycosylation?Effects of glutamine and asparagine on recombinant antibody production using CHO-GS cell lines.Fed-batch CHO cell t-PA production and feed glutamine replacement to reduce ammonia production.Reduced glutamine concentration improves protein production in growth-arrested CHO-DG44 and HEK-293E cells.Autophagy and apoptosis of recombinant Chinese hamster ovary cells during fed-batch culture: effect of nutrient supplementation.Glycosidic intermediates identified in 1H MR spectra of intact tumour cells may contribute to the clarification of aspects of glycosylation pathways.Optimization of cultivation conditions in spin tubes for Chinese hamster ovary cells producing erythropoietin and the comparison of glycosylation patterns in different cultivation vessels.Understanding of altered N-glycosylation-related gene expression in recombinant Chinese hamster ovary cells subjected to elevated ammonium concentration by digital mRNA counting.Bioprocess applications of a Sindbis virus-based temperature-inducible expression system.The effect of dissolved oxygen (DO) concentration on the glycosylation of recombinant protein produced by the insect cell-baculovirus expression system.Erythropoietin production from CHO cells grown by continuous culture in a fluidized-bed bioreactor.Plant protein hydrolysates support CHO-320 cells proliferation and recombinant IFN-gamma production in suspension and inside microcarriers in protein-free media.Enhanced erythropoietin heterogeneity in a CHO culture is caused by proteolytic degradation and can be eliminated by a high glutamine levelStabilization of cellular mitochondrial enzyme complex and sialyltransferase activity through supplementation of 30Kc19 protein.Glycosylation: An intrinsic sign of "danger"Investigation of different combinations of derivatization, separation methods and electrospray ionization mass spectrometry for standard oligosaccharides and glycans from ovalbumin.In situ Raman spectroscopy for simultaneous monitoring of multiple process parameters in mammalian cell culture bioreactors.Feeding lactate for CHO cell culture processes: impact on culture metabolism and performance.Synchronous fluorescence spectroscopy as a novel tool to enable PAT applications in bioprocesses.
P2860
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P2860
Effects of ammonia on CHO cell growth, erythropoietin production, and glycosylation.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Effects of ammonia on CHO cell growth, erythropoietin production, and glycosylation.
@en
type
label
Effects of ammonia on CHO cell growth, erythropoietin production, and glycosylation.
@en
prefLabel
Effects of ammonia on CHO cell growth, erythropoietin production, and glycosylation.
@en
P2860
P1476
Effects of ammonia on CHO cell growth, erythropoietin production, and glycosylation.
@en
P2860
P304
P356
10.1002/(SICI)1097-0290(20000520)68:4<370::AID-BIT2>3.0.CO;2-K
P577
2000-05-01T00:00:00Z