Coupling of insulin binding and insulin action on glucose transport in fat cells.
about
Insulin rapidly stimulates phosphorylation of a 46-kDa membrane protein on tyrosine residues as well as phosphorylation of several soluble proteins in intact fat cells.Abnormality of insulin binding and receptor phosphorylation in an insulin-resistant melanoma cell line.Further evidence for a two-step model of glucose-transport regulation. Inositol phosphate-oligosaccharides regulate glucose-carrier activity.Calcium-independent inhibition of glucose transport in PC-12 and L6 cells by calcium channel antagonists.Mannose, glucosamine and inositol monophosphate inhibit the effects of insulin on lipogenesis. Further evidence for a role for inositol phosphate-oligosaccharides in insulin action.Regulation of glucose carrier activity by AlCl3 and phospholipase C in fat-cells.Further evidence for the involvement of a membrane proteolytic step in insulin action.Affinity change of the adipocyte receptor fails to alter insulin-stimulated glucose transport.Inositol phospho-oligosaccharides from rat fibroblasts and adipocytes stimulate 3-O-methylglucose transport.Catecholamine-induced insulin resistance of glucose transport in isolated rat adipocytesInvolvement of hormone processing in insulin-activated glucose transport by isolated cardiac myocytes.The translocation of the glucose transporter sub-types GLUT1 and GLUT4 in isolated fat cells is differently regulated by phorbol esters.Phorbol esters imitate in rat fat-cells the full effect of insulin on glucose-carrier translocation, but not on 3-O-methylglucose-transport activity.Increased flux through the hexosamine biosynthesis pathway inhibits glucose transport acutely by activation of protein kinase C.Possible role for gp160 in constitutive but not insulin-stimulated GLUT4 trafficking: dissociation of gp160 and GLUT4 localization.Decreased tyrosine kinase activity of insulin receptor isolated from rat adipocytes rendered insulin-resistant by catecholamine treatment in vitroTiming-dependence of insulin-receptor mitogenic versus metabolic signalling: a plausible model based on coincidence of hormone and effector binding.
P2860
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P2860
Coupling of insulin binding and insulin action on glucose transport in fat cells.
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年論文
@yue
1981年論文
@zh-hant
1981年論文
@zh-hk
1981年論文
@zh-mo
1981年論文
@zh-tw
1981年论文
@wuu
1981年论文
@zh
1981年论文
@zh-cn
name
Coupling of insulin binding and insulin action on glucose transport in fat cells.
@en
type
label
Coupling of insulin binding and insulin action on glucose transport in fat cells.
@en
prefLabel
Coupling of insulin binding and insulin action on glucose transport in fat cells.
@en
P2093
P2860
P1476
Coupling of insulin binding and insulin action on glucose transport in fat cells.
@en
P2093
P2860
P304
P356
10.1152/AJPENDO.1981.240.5.E556
P407
P577
1981-05-01T00:00:00Z