Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine.
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The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids8-Aminoquinolines active against blood stage Plasmodium falciparum in vitro inhibit hematin polymerizationSulfadoxine-pyrimethamine-based combinations for malaria: a randomised blinded trial to compare efficacy, safety and selection of resistance in Malawi.In vitro culture and drug sensitivity assay of Plasmodium falciparum with nonserum substitute and acute-phase sera.Carrier-mediated partitioning of artemisinin into Plasmodium falciparum-infected erythrocytesMetabolomics and malaria biologyThe antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death.Antimalarial drug therapy: the role of parasite biology and drug resistance.Using a genome-scale metabolic network model to elucidate the mechanism of chloroquine action in Plasmodium falciparumRelationship between antimalarial drug activity, accumulation, and inhibition of heme polymerization in Plasmodium falciparum in vitro.Effect of disposition of mannich antimalarial agents on their pharmacology and toxicology.Evaluation of pH during cytostomal endocytosis and vacuolar catabolism of haemoglobin in Plasmodium falciparum.4-aminoquinoline-triazine-based hybrids with improved in vitro antimalarial activity against CQ-sensitive and CQ-resistant strains of Plasmodium falciparum.Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines.Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania majorSolid-State Characterization and Interconversion of Recrystallized Amodiaquine Dihydrochloride in Aliphatic Monohydric Alcohols.Sitamaquine sensitivity in Leishmania species is not mediated by drug accumulation in acidocalcisomes.Characterization of human cytochrome P450 mediated bioactivation of amodiaquine and its major metabolite N-desethylamodiaquine.
P2860
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P2860
Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Amodiaquine accumulation in Pl ...... ial activity over chloroquine.
@en
type
label
Amodiaquine accumulation in Pl ...... ial activity over chloroquine.
@en
prefLabel
Amodiaquine accumulation in Pl ...... ial activity over chloroquine.
@en
P2093
P921
P1476
Amodiaquine accumulation in Pl ...... ial activity over chloroquine.
@en
P2093
P356
10.1016/0166-6851(96)02655-2
P577
1996-09-01T00:00:00Z