ABC294640, a novel sphingosine kinase 2 inhibitor induces oncogenic virus infected cell autophagic death and represses tumor growth.

about

ABC294640, a novel sphingosine kinase 2 inhibitor induces oncogenic virus infected cell autophagic death and represses tumor growth.

Item

http://www.wikidata.org/entity/Q41931868

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

ABC294640, a novel sphingosine ...... th and represses tumor growth.

@en

type

Item

label

ABC294640, a novel sphingosine ...... th and represses tumor growth.

@en

prefLabel

ABC294640, a novel sphingosine ...... th and represses tumor growth.

@en

P1476

ABC294640, a novel sphingosine ...... th and represses tumor growth.

@en

P2093

Aiping Bai

http://www.w3.org/2001/XMLSchema#string

Charles D Smith

http://www.w3.org/2001/XMLSchema#string

Fangyou Yu

http://www.w3.org/2001/XMLSchema#string

Lu Dai

http://www.w3.org/2001/XMLSchema#string

Paulo C Rodriguez

http://www.w3.org/2001/XMLSchema#string

Zhiqiang Qin

http://www.w3.org/2001/XMLSchema#string

P2860

Ceramide synthases at the centre of sphingolipid metabolism and biology

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins

Up-regulation of tumor suppressor genes by exogenous dhC16-Cer contributes to its anti-cancer activity in primary effusion lymphoma.

Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression.

Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma.

Discovery and evaluation of inhibitors of human sphingosine kinase.

Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2

P31

scholarly article

P356

10.1158/1535-7163.MCT-17-0485

http://www.w3.org/2001/XMLSchema#string

P577

2017-09-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28939554

http://www.w3.org/2001/XMLSchema#string

P921

autophagy

P932

5716930

http://www.w3.org/2001/XMLSchema#string