Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses.
about
Polysaccharide A from the capsule of Bacteroides fragilis induces clonal CD4+ T cell expansion.Bacterial capsular polysaccharide prevents the onset of asthma through T-cell activation.Dendritic cell-specific Mgat2 knockout mice show antigen presentation defects but reveal an unexpected CD11c expression pattern.Myeloid glycosylation defects lead to a spontaneous common variable immunodeficiency-like condition with associated hemolytic anemia and antilymphocyte autoimmunity.
P2860
Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses.
description
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name
Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses.
@en
type
label
Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses.
@en
prefLabel
Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses.
@en
P2093
P2860
P356
P1433
P1476
Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses.
@en
P2093
Brian A Cobb
Eric Pearlman
Sean O Ryan
Sixto M Leal
P2860
P304
P356
10.1093/GLYCOB/CWT107
P577
2013-12-04T00:00:00Z