mTORC2 signaling promotes skeletal growth and bone formation in mice.
about
Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation.mTORC1 Signaling Promotes Osteoblast Differentiation from Preosteoblasts.A mouse model of craniofacial bone lesion of tuberous sclerosis complexParathyroid Hormone Reprograms Osteoblast MetabolismPTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling.Transcriptomic and epigenomic characterization of the developing bat wing.Rictor is required for optimal bone accrual in response to anti-sclerostin therapy in the mouse.Loss of Rictor with aging in osteoblasts promotes age-related bone loss.mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesisSignaling pathways regulating cartilage growth plate formation and activity.Wnt signaling and cellular metabolism in osteoblasts.Bone Cell Bioenergetics and Skeletal Energy Homeostasis.Actin up in the Nucleus: Regulation of Actin Structures Modulates Mesenchymal Stem Cell Differentiation.Genetic Dissection of Trabecular Bone Structure with Mouse Intersubspecific Consomic Strains.Glucocorticoid Suppresses Connexin 43 Expression by Inhibiting the Akt/mTOR Signaling Pathway in Osteoblasts.Abaloparatide, a novel PTH receptor agonist, increased bone mass and strength in ovariectomized cynomolgus monkeys by increasing bone formation without increasing bone resorption.Increased Ca2+ signaling through CaV1.2 promotes bone formation and prevents estrogen deficiency-induced bone loss.Inhibition of Mammalian Target of Rapamycin Signaling with Rapamycin Prevents Trauma-Induced Heterotopic Ossification.mTOR signaling in skeletal development and disease.Glucose metabolism in bone.Energy Metabolism of the Osteoblast: Implications for Osteoporosis.mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis.Ablation of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development.Integrating genome-wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin-Beck disease and primary osteoarthritis.DEPTOR regulates osteogenic differentiation via inhibiting MEG3-mediated activation of BMP4 signaling and is involved in osteoporosis.Osteogenesis and aging: lessons from mesenchymal stem cellsNUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts
P2860
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P2860
mTORC2 signaling promotes skeletal growth and bone formation in mice.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
mTORC2 signaling promotes skeletal growth and bone formation in mice.
@en
type
label
mTORC2 signaling promotes skeletal growth and bone formation in mice.
@en
prefLabel
mTORC2 signaling promotes skeletal growth and bone formation in mice.
@en
P2093
P2860
P356
P1476
mTORC2 signaling promotes skeletal growth and bone formation in mice.
@en
P2093
Fanxin Long
Jianquan Chen
Matthew J Silva
Nilsson Holguin
P2860
P304
P356
10.1002/JBMR.2348
P577
2015-02-01T00:00:00Z