EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway.
about
Nickel and the microbial toxin, MALP-2, stimulate proangiogenic mediators from human lung fibroblasts via a HIF-1alpha and COX-2-mediated pathwayKaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasionParicalcitol Pretreatment Attenuates Renal Ischemia-Reperfusion Injury via Prostaglandin E2 Receptor EP4 Pathway.NFAT and CREB regulate Kaposi's sarcoma-associated herpesvirus-induced cyclooxygenase 2 (COX-2)Sirt1 activation protects the mouse renal medulla from oxidative injury.Paricalcitol attenuates lipopolysaccharide-induced inflammation and apoptosis in proximal tubular cells through the prostaglandin E2 receptor EP4.Hypoxia and prostaglandin E receptor 4 signalling pathways synergise to promote endometrial adenocarcinoma cell proliferation and tumour growth.Prostaglandin E2 receptors in asthma and in chronic rhinosinusitis/nasal polyps with and without aspirin hypersensitivity.Pleiotropic effects of prostaglandin E2 in hematopoiesis; prostaglandin E2 and other eicosanoids regulate hematopoietic stem and progenitor cell function.Prostaglandin E2 receptor EP4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem-like cell functionsNovel link between prostaglandin E2 (PGE2) and cholinergic signaling in lung cancer: The role of c-Jun in PGE2-induced α7 nicotinic acetylcholine receptor expression and tumor cell proliferationDisruption of cyclooxygenase type 2 exacerbates apoptosis and renal damage during obstructive nephropathyEffect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice.Cytosolic phospholipase A2α regulates G1 progression through modulating FOXO1 activityA prostaglandin E (PGE) receptor EP4 antagonist protects natural killer cells from PGE2-mediated immunosuppression and inhibits breast cancer metastasis.Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2 and LXA4 in the induction of macrophage death.Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis.Antagonism of the prostaglandin E receptor EP4 inhibits metastasis and enhances NK functionProstaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation.Reciprocal cross-talk between Prostaglandin E2 and bone in prostate cancer: a current review.Osteocytes and WNT: the mechanical control of bone formation.Therapeutic implications of disorders of cell death signalling: membranes, micro-environment, and eicosanoid and docosanoid metabolismProstaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells.Cyclooxygenase-2 positively regulates Akt signalling and enhances survival of erythroleukemia cells exposed to anticancer agents.Targeting COX-2 and EP4 to control tumor growth, angiogenesis, lymphangiogenesis and metastasis to the lungs and lymph nodes in a breast cancer model.PGE(2) is a UVR-inducible autocrine factor for human melanocytes that stimulates tyrosinase activation.Genetic variations in the PRKAA1 and ZBTB20 genes and gastric cancer susceptibility in a Korean population.Expression of prostaglandin E2 and EP receptors in human papillary thyroid carcinoma.COX-2 induces oncogenic micro RNA miR655 in human breast cancer.COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis.Pulse exposure of haematopoietic grafts to prostaglandin E2 in vitro facilitates engraftment and recovery.MiRNA-206 suppresses PGE2-induced colorectal cancer cell proliferation, migration, and invasion by targetting TM4SF1
P2860
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P2860
EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway.
@en
type
label
EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway.
@en
prefLabel
EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway.
@en
P2093
P2860
P1476
EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway.
@en
P2093
Courtney W Houchen
Mark A Sturmoski
Robert J George
Shrikant Anant
P2860
P304
P356
10.1016/J.PROSTAGLANDINS.2006.10.005
P577
2007-01-03T00:00:00Z