The antimalarial drug quinine disrupts Tat2p-mediated tryptophan transport and causes tryptophan starvation.
about
Uptake of inorganic phosphate is a limiting factor for Saccharomyces cerevisiae during growth at low temperatures.The essential iron-sulfur protein Rli1 is an important target accounting for inhibition of cell growth by reactive oxygen species.Yeast toxicogenomics: genome-wide responses to chemical stresses with impact in environmental health, pharmacology, and biotechnologyFunctional profiling discovers the dieldrin organochlorinated pesticide affects leucine availability in yeastFunctional expression of parasite drug targets and their human orthologs in yeastCompound prioritization methods increase rates of chemical probe discovery in model organisms.Chromate-induced sulfur starvation and mRNA mistranslation in yeast are linked in a common mechanism of Cr toxicityRegulation of yeast nutrient permease endocytosis by ATP-binding cassette transporters and a seven-transmembrane protein, RSB1.A Label-free Sirtuin 1 Assay based on Droplet-Electrospray Ionization Mass SpectrometryActin-mediated endocytosis limits intracellular Cr accumulation and Cr toxicity during chromate stress.The antimalarial drug quinine interferes with serotonin biosynthesis and action.The utility of yeast as a tool for cell-based, target-directed high-throughput screening.The Candidate Antimalarial Drug MMV665909 Causes Oxygen-Dependent mRNA Mistranslation and Synergizes with Quinoline-Derived Antimalarials.Cell wall perturbation sensitizes fungi to the antimalarial drug chloroquine.Quinine interactions with tryptophan and tyrosine in malaria patients, and implications for quinine responses in the clinical setting.Novel, Synergistic Antifungal Combinations that Target Translation Fidelity.Mitochondrial Ferredoxin Determines Vulnerability of Cells to Copper Excess.Oral quinine sulfate for the treatment of electrical storm and prevention of recurrent shocks in Brugada syndrome after failed cilostazol therapy.A genome-wide screen identifies yeast genes required for protection against or enhanced cytotoxicity of the antimalarial drug quinine.Heterologous Expression of a Novel Drug Transporter from the Malaria Parasite Alters Resistance to Quinoline Antimalarials.Novel Combinations of Agents Targeting Translation That Synergistically Inhibit Fungal Pathogens
P2860
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P2860
The antimalarial drug quinine disrupts Tat2p-mediated tryptophan transport and causes tryptophan starvation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
The antimalarial drug quinine ...... causes tryptophan starvation.
@en
type
label
The antimalarial drug quinine ...... causes tryptophan starvation.
@en
prefLabel
The antimalarial drug quinine ...... causes tryptophan starvation.
@en
P2860
P356
P1476
The antimalarial drug quinine ...... causes tryptophan starvation.
@en
P2093
Combiz Khozoie
P2860
P304
17968-17974
P356
10.1074/JBC.M109.005843
P407
P577
2009-05-05T00:00:00Z