RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis.
about
Open access chemical probes for epigenetic targetsPancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.Imaging tumor metabolism using positron emission tomographyMolecular pathways and targets in prostate cancerThe biology of castration-resistant prostate cancerMYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2.The converging roles of BRD4 and gene transcription in pluripotency and oncogenesisRegulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival.The metabolic co-regulator PGC1α suppresses prostate cancer metastasis.Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy.Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate CancerTherapeutic Approaches Targeting MYC-Driven Prostate CancerThe nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein.Cellular determinants and microenvironmental regulation of prostate cancer metastasis.Real-Time Transferrin-Based PET Detects MYC-Positive Prostate Cancer.Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome.A Versatile Gene Delivery System for Efficient and Tumor Specific Gene Manipulation in vivo.Molecular determinants of prostate cancer metastasis.MYC leads the way.Single-cell sequencing deciphers a convergent evolution of copy number alterations from primary to circulating tumor cells.Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells.Genetics and biology of prostate cancerVirus Delivery of CRISPR Guides to the Murine Prostate for Gene Alteration
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P2860
RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
RapidCaP, a novel GEM model fo ...... ver of Pten-mutant metastasis.
@en
type
label
RapidCaP, a novel GEM model fo ...... ver of Pten-mutant metastasis.
@en
prefLabel
RapidCaP, a novel GEM model fo ...... ver of Pten-mutant metastasis.
@en
P2093
P2860
P1433
P1476
RapidCaP, a novel GEM model fo ...... ver of Pten-mutant metastasis.
@en
P2093
Brian D Robinson
Hyejin Cho
James E Bradner
John E Wilkinson
Lloyd C Trotman
Mireia Castillo-Martin
Tali Herzka
P2860
P304
P356
10.1158/2159-8290.CD-13-0346
P577
2014-01-20T00:00:00Z