Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene
about
A critical role for the transcription factor Scl in platelet production during stress thrombopoiesisTargets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1Corepressor Rcor1 is essential for murine erythropoiesisMef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasisThe essential haematopoietic transcription factor Scl is also critical for neuronal developmentNovel insights into the genetic controls of primitive and definitive hematopoiesis from zebrafish modelsStress hematopoiesis is regulated by the Krüppel-like transcription factor ZBP-89.Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation.Gfi-1 regulates the erythroid transcription factor network through Id2 repression in murine hematopoietic progenitor cells.Murine erythroid short-term radioprotection requires a BMP4-dependent, self-renewing population of stress erythroid progenitors.During EPO or anemia challenge, erythroid progenitor cells transit through a selectively expandable proerythroblast poolTranscriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cellsConstitutive phosphorylation of GATA-1 at serine²⁶ attenuates the colony-forming activity of erythrocyte-committed progenitors.In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitors.T-cell acute leukemia 1 (TAL1) regulation of erythropoietin receptor and association with excessive erythrocytosis.Transcriptional activators, repressors, and epigenetic modifiers controlling hematopoietic stem cell development.Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation.Concise review: Blood relatives: formation and regulation of hematopoietic stem cells by the basic helix-loop-helix transcription factors stem cell leukemia and lymphoblastic leukemia-derived sequence 1.Epigenetic and genetic mechanisms in red cell biology.Hematopoietic transcriptional mechanisms: from locus-specific to genome-wide vantage points.PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation.Impaired in vitro erythropoiesis following deletion of the Scl (Tal1) +40 enhancer is largely compensated for in vivo despite a significant reduction in expressionGenome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells.Hematopoietic transcription factors and differential cofactor binding regulate PRKACB isoform expression.
P2860
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P2860
Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Functional but abnormal adult ...... of the stem cell leukemia gene
@en
type
label
Functional but abnormal adult ...... of the stem cell leukemia gene
@en
prefLabel
Functional but abnormal adult ...... of the stem cell leukemia gene
@en
P2093
P2860
P1476
Functional but abnormal adult ...... of the stem cell leukemia gene
@en
P2093
C Glenn Begley
Jessica M Salmon
Leonie J Van Stekelenburg
Mark A Hall
Matthew P McCormack
Nicholas J Slater
Stephen M Jane
P2860
P304
P356
10.1128/MCB.25.15.6355-6362.2005
P407
P577
2005-08-01T00:00:00Z