Interferon-γ induces progressive nigrostriatal degeneration and basal ganglia calcification.
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Differential Co-Expression between α-Synuclein and IFN-γ Signaling Genes across Development and in Parkinson’s DiseaseMHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degenerationCapsid serotype and timing of injection determines AAV transduction in the neonatal mice brain.Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration.Microglia-Derived Cytokines/Chemokines Are Involved in the Enhancement of LPS-Induced Loss of Nigrostriatal Dopaminergic Neurons in DJ-1 Knockout Mice.Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases.Parkinson's disease and enhanced inflammatory response.Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disordersInflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice.Rapamycin upregulates glutamate transporter and IL-6 expression in astrocytes in a mouse model of Parkinson's disease.The immunological challenges of cell transplantation for the treatment of Parkinson's disease.Review: microglia in protein aggregation disorders: friend or foe?Network modeling to identify new mechanisms and therapeutic targets for Parkinson's disease.PDGF, pericytes and the pathogenesis of idiopathic basal ganglia calcification (IBGC).Neuronal MHC-I expression and its implications in synaptic function, axonal regeneration and Parkinson's and other brain diseasesCandidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease.Interferon Gamma potentiates the injury caused by MPP(+) on SH-SY5Y cells, which is attenuated by the nitric oxide synthases inhibition.Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.TGFβ1 inhibits IFNγ-mediated microglia activation and protects mDA neurons from IFNγ-driven neurotoxicity.Ifngr1 and Stat1 mediated canonical Ifn-γ signaling drives nigrostriatal degeneration.Microglial-induced Müller cell gliosis is attenuated by progesterone in a mouse model of retinitis pigmentosa.
P2860
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P2860
Interferon-γ induces progressive nigrostriatal degeneration and basal ganglia calcification.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Interferon-γ induces progressi ...... d basal ganglia calcification.
@en
type
label
Interferon-γ induces progressi ...... d basal ganglia calcification.
@en
prefLabel
Interferon-γ induces progressi ...... d basal ganglia calcification.
@en
P2093
P2860
P356
P1433
P1476
Interferon-γ induces progressi ...... d basal ganglia calcification.
@en
P2093
Amanda Beccard
Carolina Ceballos-Diaz
Christopher Janus
Karen Jansen-West
Paramita Chakrabarty
Pritam Das
Todd E Golde
Wen-Lang Lin
P2860
P2888
P304
P356
10.1038/NN.2829
P407
P577
2011-05-15T00:00:00Z
P5875
P6179
1020440871