A non-natural variant of human lysozyme (I59T) mimics the in vitro behaviour of the I56T variant that is responsible for a form of familial amyloidosis.
about
Protease-activated alpha-2-macroglobulin can inhibit amyloid formation via two distinct mechanismsA Nanobody Binding to Non-Amyloidogenic Regions of the Protein Human Lysozyme Enhances Partial Unfolding but Inhibits Amyloid Fibril FormationLocal cooperativity in an amyloidogenic state of human lysozyme observed at atomic resolution.Analysis of the native structure, stability and aggregation of biotinylated human lysozyme.Protein amyloids develop an intrinsic fluorescence signature during aggregation.Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster.A method for rapid high-throughput biophysical analysis of proteins.Population of nonnative states of lysozyme variants drives amyloid fibril formation.Structure of a low-population intermediate state in the release of an enzyme product.Application of Lysine-specific Labeling to Detect Transient Interactions Present During Human Lysozyme Amyloid Fibril Formation.The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme.Hereditary Lysozyme Amyloidosis Variant p.Leu102Ser Associates with Unique Phenotype.BDB: databank of PDB files with consistent B-factors.
P2860
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P2860
A non-natural variant of human lysozyme (I59T) mimics the in vitro behaviour of the I56T variant that is responsible for a form of familial amyloidosis.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
A non-natural variant of human ...... form of familial amyloidosis.
@en
type
label
A non-natural variant of human ...... form of familial amyloidosis.
@en
prefLabel
A non-natural variant of human ...... form of familial amyloidosis.
@en
P2093
P2860
P356
P1476
A non-natural variant of human ...... form of familial amyloidosis.
@en
P2093
Anne Dhulesia
Christine L Hagan
Erwin De Genst
Janet R Kumita
Janice Dumont
John Christodoulou
Mireille Dumoulin
Russell J K Johnson
P2860
P304
P356
10.1093/PROTEIN/GZQ023
P577
2010-04-09T00:00:00Z