Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins.
about
Perlecan controls neurogenesis in the developing telencephalonSkeletal muscle laminin and MDC1A: pathogenesis and treatment strategies.Form and function: the laminin family of heterotrimersThe type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparinMutations in B3GALNT2 cause congenital muscular dystrophy and hypoglycosylation of α-dystroglycanRibozyme-mediated perlecan knockdown impairs chondrogenic differentiation of C3H10T1/2 fibroblasts.Developmental and pathogenic mechanisms of basement membrane assemblyStructure of the C-terminal laminin G-like domain pair of the laminin alpha2 chain harbouring binding sites for alpha-dystroglycan and heparinPost-translational maturation of dystroglycan is necessary for pikachurin binding and ribbon synaptic localizationA central function for perlecan in skeletal muscle and cardiovascular developmentLaminin isoforms containing the gamma3 chain are unable to bind to integrins due to the absence of the glutamic acid residue conserved in the C-terminal regions of the gamma1 and gamma2 chainsThe dystroglycan complex is necessary for stabilization of acetylcholine receptor clusters at neuromuscular junctions and formation of the synaptic basement membraneThe fibulin-1 gene (FBLN1) is disrupted in a t(12;22) associated with a complex type of synpolydactylyThe small leucine-rich repeat proteoglycan biglycan binds to alpha-dystroglycan and is upregulated in dystrophic musclePerlecan maintains the integrity of cartilage and some basement membranesA stoichiometric complex of neurexins and dystroglycan in brainCrystal structure of the second LNS/LG domain from neurexin 1alpha: Ca2+ binding and the effects of alternative splicingThe potential of sarcospan in adhesion complex replacement therapeutics for the treatment of muscular dystrophyLaminin isoforms in endothelial and perivascular basement membranesThe dynamic architecture of photoreceptor ribbon synapses: cytoskeletal, extracellular matrix, and intramembrane proteinsDistinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiencyCrystal structure of a C-terminal fragment of growth arrest-specific protein Gas6. Receptor tyrosine kinase activation by laminin G-like domainsCrystal Structure and Cell Surface Anchorage Sites of Laminin 1LG4-5Crystal structure of the N-terminal NC4 domain of collagen IX, a zinc binding member of the laminin-neurexin-sex hormone binding globulin (LNS) domain familyThe Laminin 511/521 binding site on the Lutheran blood group glycoprotein is located at the flexible junction of Ig domains 2 and 3Expression of gamma -sarcoglycan in smooth muscle and its interaction with the smooth muscle sarcoglycan-sarcospan complexIntegrins as receptors for lamininsSpatial regulation and activity modulation of plasmin by high affinity binding to the G domain of the alpha 3 subunit of laminin-5Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteinsA unique sequence of the laminin alpha 3 G domain binds to heparin and promotes cell adhesion through syndecan-2 and -4The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchorLaminin-6 assembles into multimolecular fibrillar complexes with perlecan and participates in mechanical-signal transduction via a dystroglycan-dependent, integrin-independent mechanismGlycosylation defects: a new mechanism for muscular dystrophy?Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2Dystroglycan organizes axon guidance cue localization and axonal pathfindingThe Dystrophin Complex: Structure, Function, and Implications for TherapyAdvanced glycation end-products and their receptor-mediated roles: inflammation and oxidative stress.Basal lamina strengthens cell membrane integrity via the laminin G domain-binding motif of alpha-dystroglycanStructural basis of laminin binding to the LARGE glycans on dystroglycan.Beta1 integrin and alpha-dystroglycan binding sites are localized to different laminin-G-domain-like (LG) modules within the laminin alpha5 chain G domain.
P2860
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P2860
Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Binding of the G domains of la ...... extracellular matrix proteins.
@en
Binding of the G domains of la ...... extracellular matrix proteins.
@nl
type
label
Binding of the G domains of la ...... extracellular matrix proteins.
@en
Binding of the G domains of la ...... extracellular matrix proteins.
@nl
prefLabel
Binding of the G domains of la ...... extracellular matrix proteins.
@en
Binding of the G domains of la ...... extracellular matrix proteins.
@nl
P2093
P2860
P356
P1433
P1476
Binding of the G domains of la ...... extracellular matrix proteins.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/18.4.863
P407
P577
1999-02-01T00:00:00Z