Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration.
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Lost in translation: preclinical studies on 3,4-methylenedioxymethamphetamine provide information on mechanisms of action, but do not allow accurate prediction of adverse events in humansThe pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to ratsThe mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')-induced degeneration of 5-HT nerve endings in rat brainA study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brainEcstasy: are animal data consistent between species and can they translate to humans?Catechol-o-methyltransferase and 3,4-({+/-})-methylenedioxymethamphetamine toxicity.Functional consequences of perinatal exposure to 3,4-methylenedioxymethamphetamine in rat brain.Gene expression analysis indicates CB1 receptor upregulation in the hippocampus and neurotoxic effects in the frontal cortex 3 weeks after single-dose MDMA administration in Dark Agouti rats.A clinical crossroads for MDMA.The recreational drug ecstasy disrupts the hypothalamic-pituitary-gonadal reproductive axis in adult male rats.Inhibition of the dorsomedial hypothalamus, but not the medullary raphe pallidus, decreases hyperthermia and mortality from MDMA given in a warm environment.Pharmacokinetics and pharmacodynamics of 3,4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug-drug interactions.MDMA-induced neurotoxicity: long-term effects on 5-HT biosynthesis and the influence of ambient temperature.Effect of acute brain tyrosine depletion on MDMA-induced changes in brain 5-HT.Protection against 3,4-methylenedioxymethamphetamine-induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia.Increased interleukin-1β levels following low dose MDMA induces tolerance against the 5-HT neurotoxicity produced by challenge MDMA.Studies, using in vivo microdialysis, on the effect of the dopamine uptake inhibitor GBR 12909 on 3,4-methylenedioxymethamphetamine ('ecstasy')-induced dopamine release and free radical formation in the mouse striatum.Elevation of ambient room temperature has differential effects on MDMA-induced 5-HT and dopamine release in striatum and nucleus accumbens of rats.MDMA as a clinical tool: a note of caution. A response to Sessa and Nutt.Studies on striatal neurotoxicity caused by the 3,4-methylenedioxymethamphetamine/ malonate combination: implications for serotonin/dopamine interactions.The acute and long-term neurotoxic effects of MDMA on marble burying behaviour in mice.(±)-MDMA and its enantiomers: potential therapeutic advantages of R(-)-MDMA.Investigation of the mechanisms mediating MDMA "Ecstasy"-induced increases in cerebro-cortical perfusion determined by btASL MRI.Assessing the role of dopamine in the differential neurotoxicity patterns of methamphetamine, mephedrone, methcathinone and 4-methylmethamphetamine.Gene expression analysis indicates reduced memory and cognitive functions in the hippocampus and increase in synaptic reorganization in the frontal cortex 3 weeks after MDMA administration in Dark Agouti rats
P2860
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P2860
Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Studies on the role of dopamin ...... or 'ecstasy') administration.
@en
Studies on the role of dopamin ...... or 'ecstasy') administration.
@nl
type
label
Studies on the role of dopamin ...... or 'ecstasy') administration.
@en
Studies on the role of dopamin ...... or 'ecstasy') administration.
@nl
prefLabel
Studies on the role of dopamin ...... or 'ecstasy') administration.
@en
Studies on the role of dopamin ...... or 'ecstasy') administration.
@nl
P2093
P2860
P356
P1476
Studies on the role of dopamin ...... or 'ecstasy') administration.
@en
P2093
P2860
P304
P356
10.1038/SJ.BJP.0702373
P407
P577
1999-02-01T00:00:00Z