SsrA-mediated trans-translation plays a role in mRNA quality control by facilitating degradation of truncated mRNAs.
about
The fail-safe system to rescue the stalled ribosomes in Escherichia coliHuman mitochondrial SUV3 and polynucleotide phosphorylase form a 330-kDa heteropentamer to cooperatively degrade double-stranded RNA with a 3'-to-5' directionalityToxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotesCompetition between trans-translation and termination or elongation of translation.The tmRNA ribosome-rescue systemStructural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the RibosomeIdentification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJThe SmpB-tmRNA tagging system plays important roles in Streptomyces coelicolor growth and developmentRibosomal protein S12 and aminoglycoside antibiotics modulate A-site mRNA cleavage and transfer-messenger RNA activity in Escherichia coliParticipation of 3'-to-5' exoribonucleases in the turnover of Bacillus subtilis mRNAResolving nonstop translation complexes is a matter of life or death.The N-terminus of GalE induces tmRNA activity in Escherichia coli.tmRNA is essential in Shigella flexneri.YaeJ is a novel ribosome-associated protein in Escherichia coli that can hydrolyze peptidyl-tRNA on stalled ribosomes.tmRNA regulates synthesis of the ArfA ribosome rescue factorA-site mRNA cleavage is not required for tmRNA-mediated ssrA-peptide tagging.tmRNA determinants required for facilitating nonstop mRNA decay.Translation of nonSTOP mRNA is repressed post-initiation in mammalian cellsTranslational regulation of the Escherichia coli stress factor RpoS: a role for SsrA and LonYoeB toxin is activated during thermal stress.Proteomic identification of tmRNA substratesProteobacterial ArfA peptides are synthesized from non-stop messenger RNAs.Quality control of bacterial mRNA decoding and decay.Functional SmpB-ribosome interactions require tmRNA.RNase II is important for A-site mRNA cleavage during ribosome pausing.Beyond ribosome rescue: tmRNA and co-translational processesA ribosome profiling study of mRNA cleavage by the endonuclease RelE.tRNA/mRNA Mimicry by tmRNA and SmpB in Trans-TranslationMechanism of trans-translation revealed by in vitro studies.tmRNA-mediated trans-translation as the major ribosome rescue system in a bacterial cellBiochemical aspects of bacterial strategies for handling the incomplete translation processes.A minimum structure of aminoglycosides that causes an initiation shift of trans-translationNascent-peptide-mediated ribosome stalling at a stop codon induces mRNA cleavage resulting in nonstop mRNA that is recognized by tmRNA.Functional significance of an evolutionarily conserved alanine (GCA) resume codon in tmRNA in Escherichia coliImportance of the tmRNA system for cell survival when transcription is blocked by DNA-protein cross-links.Translation of aberrant mRNAs lacking a termination codon or with a shortened 3'-UTR is repressed after initiation in yeast.SsrA tagging of Escherichia coli SecM at its translation arrest sequence.Prolyl-tRNA(Pro) in the A-site of SecM-arrested ribosomes inhibits the recruitment of transfer-messenger RNA.Protein tagging at rare codons is caused by tmRNA action at the 3' end of nonstop mRNA generated in response to ribosome stalling.Trans-translation is involved in the CcpA-dependent tagging and degradation of TreP in Bacillus subtilis.
P2860
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P2860
SsrA-mediated trans-translation plays a role in mRNA quality control by facilitating degradation of truncated mRNAs.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
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2003年學術文章
@zh-hant
name
SsrA-mediated trans-translatio ...... egradation of truncated mRNAs.
@en
SsrA-mediated trans-translatio ...... egradation of truncated mRNAs.
@nl
type
label
SsrA-mediated trans-translatio ...... egradation of truncated mRNAs.
@en
SsrA-mediated trans-translatio ...... egradation of truncated mRNAs.
@nl
prefLabel
SsrA-mediated trans-translatio ...... egradation of truncated mRNAs.
@en
SsrA-mediated trans-translatio ...... egradation of truncated mRNAs.
@nl
P2093
P2860
P356
P1433
P1476
SsrA-mediated trans-translatio ...... egradation of truncated mRNAs.
@en
P2093
Hiroji Aiba
Kaoru Jojima
Takafumi Sunohara
Toshifumi Inada
Yasufumi Yamamoto
P2860
P304
P356
10.1261/RNA.2174803
P407
P577
2003-04-01T00:00:00Z