Stochastic but highly coordinated protein unfolding and translocation by the ClpXP proteolytic machine.
about
Cellobiohydrolase 1 from Trichoderma reesei degrades cellulose in single cellobiose stepsCapturing the mechanical unfolding pathway of a large protein with coiled-coil probes.Unfolding the mechanism of the AAA+ unfoldase VAT by a combined cryo-EM, solution NMR study.Mechanochemical basis of protein degradation by a double-ring AAA+ machineAssaying the kinetics of protein denaturation catalyzed by AAA+ unfolding machines and proteasesSubunit asymmetry and roles of conformational switching in the hexameric AAA+ ring of ClpXCoarse-Grained Simulations of Topology-Dependent Mechanisms of Protein Unfolding and Translocation Mediated by ClpY ATPase NanomachinesUnique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy.Conformational Changes in the Endosomal Sorting Complex Required for the Transport III Subunit Ist1 Lead to Distinct Modes of ATPase Vps4 RegulationTwo-subunit DNA escort mechanism and inactive subunit bypass in an ultra-fast ring ATPase.Sclerotiamide: The First Non-Peptide-Based Natural Product Activator of Bacterial Caseinolytic Protease P.Time-resolved neutron scattering provides new insight into protein substrate processing by a AAA+ unfoldaseOrigin and Functional Evolution of the Cdc48/p97/VCP AAA+ Protein Unfolding and Remodeling Machine.Mechanistic insights into bacterial AAA+ proteases and protein-remodelling machines.Mini review: ATP-dependent proteases in bacteria.Identification and Characterization of Differentially-Regulated Type IVb Pilin Genes Necessary for Predation in Obligate Bacterial PredatorsRegulated Proteolysis in Bacteria: Caulobacter.AAA-ATPases in Protein Degradation.ATP binding to neighbouring subunits and intersubunit allosteric coupling underlie proteasomal ATPase function.Comparative Analysis of the Structure and Function of AAA+ Motors ClpA, ClpB, and Hsp104: Common Threads and Disparate Functions.Drosophila protease ClpXP specifically degrades DmLRPPRC1 controlling mitochondrial mRNA and translation.Highly Dynamic Interactions Maintain Kinetic Stability of the ClpXP Protease During the ATP-Fueled Mechanical Cycle.The ClpXP protease is dispensable for degradation of unfolded proteins in Staphylococcus aureus.Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine.Dissection of Axial-Pore Loop Function during Unfolding and Translocation by a AAA+ Proteolytic Machine.Proteolytic control of the mitochondrial calcium uniporter complex.Full molecular trajectories of RNA polymerase at single base-pair resolution.Effect of directional pulling on mechanical protein degradation by ATP-dependent proteolytic machines.The force-dependent mechanism of DnaK-mediated mechanical folding.Covalently linked HslU hexamers support a probabilistic mechanism that links ATP hydrolysis to protein unfolding and translocation.Mechanically Watching the ClpXP Proteolytic Machinery.Regulated Proteolysis in Bacteria.Single-molecule peptide fingerprinting.Modeling the effects of lattice defects on microtubule breaking and healing.Folding-Degradation Relationship of a Membrane Protein Mediated by the Universally Conserved ATP-Dependent Protease FtsH.Protein folding in the cell, from atom to organism
P2860
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P2860
Stochastic but highly coordinated protein unfolding and translocation by the ClpXP proteolytic machine.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Stochastic but highly coordina ...... the ClpXP proteolytic machine.
@en
Stochastic but highly coordina ...... the ClpXP proteolytic machine.
@nl
type
label
Stochastic but highly coordina ...... the ClpXP proteolytic machine.
@en
Stochastic but highly coordina ...... the ClpXP proteolytic machine.
@nl
prefLabel
Stochastic but highly coordina ...... the ClpXP proteolytic machine.
@en
Stochastic but highly coordina ...... the ClpXP proteolytic machine.
@nl
P2093
P2860
P1433
P1476
Stochastic but highly coordina ...... the ClpXP proteolytic machine
@en
P2093
Adrian O Olivares
Benjamin M Stinson
Juan Carlos Cordova
Karl R Schmitz
Marie-Eve Aubin-Tam
Matthew J Lang
Tania A Baker
Yongdae Shin
P2860
P304
P356
10.1016/J.CELL.2014.05.043
P407
P577
2014-07-01T00:00:00Z