Unique agonist-bound cannabinoid CB1 receptor conformations indicate agonist specificity in signaling.
about
Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.The year in G protein-coupled receptor research.Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery?Type 1 cannabinoid receptor ligands display functional selectivity in a cell culture model of striatal medium spiny projection neurons.The potential for selective pharmacological therapies through biased receptor signalingThe significance of G protein-coupled receptor crystallography for drug discovery.Plasmon-waveguide resonance (PWR) spectroscopy for directly viewing rates of GPCR/G-protein interactions and quantifying affinities.CB(1) receptor allosteric modulators display both agonist and signaling pathway specificity.Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptorsDiscriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog.Discriminative stimulus functions of methanandamide and delta(9)-THC in rats: tests with aminoalkylindoles (WIN55,212-2 and AM678) and ethanol.Probing heterotrimeric G protein activation: applications to biased ligands.New concepts in pharmacological efficacy at 7TM receptors: IUPHAR review 2.Atypical Endocannabinoid Signaling Initiates a New Form of Memory-Related Plasticity at a Cortical Input to Hippocampus.Identification of a novel protein-protein interaction motif mediating interaction of GPCR-associated sorting proteins with G protein-coupled receptors.Dual neuroprotective and neurotoxic effects of cannabinoid drugs in vitro.Reciprocal influences of CB1 cannabinoid receptor agonists on ERK and JNK signalling in N1E-115 cells.Ligand activation induces different conformational changes in CXCR3 receptor isoforms as evidenced by plasmon waveguide resonance (PWR).Cannabinoid CB1 and CB2 Receptor Signaling and BiasPlasmon-waveguide resonance studies of ligand binding to integral proteins in membrane fragments derived from bacterial and mammalian cells.The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors.CB1 and CB2 Receptor Pharmacology.Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1-CB2 Heteroreceptor Complexes.
P2860
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P2860
Unique agonist-bound cannabinoid CB1 receptor conformations indicate agonist specificity in signaling.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Unique agonist-bound cannabino ...... nist specificity in signaling.
@en
Unique agonist-bound cannabino ...... nist specificity in signaling.
@nl
type
label
Unique agonist-bound cannabino ...... nist specificity in signaling.
@en
Unique agonist-bound cannabino ...... nist specificity in signaling.
@nl
prefLabel
Unique agonist-bound cannabino ...... nist specificity in signaling.
@en
Unique agonist-bound cannabino ...... nist specificity in signaling.
@nl
P2093
P2860
P921
P1476
Unique agonist-bound cannabino ...... nist specificity in signaling.
@en
P2093
Chad K Park
Dagmar Stropova
Gordon Tollin
Henry I Yamamura
Savitha Devanathan
Teodora Georgieva
Victor J Hruby
William R Roeske
Zdzislaw Salamon
P2860
P356
10.1016/J.EJPHAR.2007.11.053
P407
P577
2007-11-28T00:00:00Z