Inhibitors of monoacylglycerol lipase, fatty-acid amide hydrolase and endocannabinoid transport differentially suppress capsaicin-induced behavioral sensitization through peripheral endocannabinoid mechanisms.
about
Chemical probes of endocannabinoid metabolismA lipid gate for the peripheral control of painMonoacylglycerol lipase - a target for drug development?Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in MiceGenetic influences on the neural and physiological bases of acute threat: A research domain criteria (RDoC) perspective.Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain.Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in ratsSelective monoacylglycerol lipase inhibitors: antinociceptive versus cannabimimetic effects in miceFatty acid-binding proteins transport N-acylethanolamines to nuclear receptors and are targets of endocannabinoid transport inhibitors.Impact of Genetic Reduction of NMNAT2 on Chemotherapy-Induced Losses in Cell Viability In Vitro and Peripheral Neuropathy In VivoAlterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics folloConvergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivityCharacterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons.The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model.Increased anandamide uptake by sensory neurons contributes to hyperalgesia in a model of cancer painImplication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6.In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects.Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord.Anandamide and 2-arachidonoylglycerol: pharmacological properties, functional features, and emerging specificities of the two major endocannabinoids.Dynamic changes to the endocannabinoid system in models of chronic pain.Endocannabinoid system and pain: an introduction.Cannabinoids in pain management: CB1, CB2 and non-classic receptor ligands.Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain.Getting high on the endocannabinoid system.Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat.Differences in peripheral endocannabinoid modulation of scratching behavior in facial vs. spinally-innervated skin
P2860
Q26863202-7F67A4D5-DE92-4A61-8ADF-8F1E7DB74BB4Q26995053-A6A09840-FEFF-45B4-A44B-B43C97499A9FQ26998964-98E7AF86-A9E7-492A-A11D-77392F4CFA27Q28262282-B028CC46-6434-43B7-9F84-1D9A3FC278B4Q30366575-89950587-FFA7-4069-869C-C1788568AD24Q35013497-43F87BDB-5331-404F-9480-49CEBA206EE1Q35119719-34DF3ACA-028D-4036-B3AC-42C4CC4AB120Q35531804-E545296F-47E4-4C1B-8680-A29171ADC4EAQ35728434-2CF50973-B01F-47D0-B73F-632BAAD80AFFQ35903899-E6293CFF-318B-4BAC-B375-B5920C51AB70Q36476481-D11E1C6A-F058-480C-8258-2531BAA54AC8Q36546326-372E76E4-9720-40E5-AD3B-7DB55CC9B0ADQ36990269-040F7249-8B0B-4311-924A-191D06588E96Q37030457-F3EA873B-7551-4317-8646-B97696AD4A1BQ37107118-D1505E78-376A-4912-BD8C-F90997AAF71DQ37256080-99005814-C498-40DB-9E6F-D49C1F87A2D9Q37637750-4A0EA4C6-AABC-4F47-9401-64A33F2D28C7Q37691232-EB8F9AE4-3DE7-4409-BB17-190DC68A4568Q38026790-3FE2B62E-CD3F-4620-A0C6-A9A739023C10Q38056398-B52A56AD-0663-4F0A-A909-C34F76A98979Q38154691-830FE6C4-7925-4B7C-A572-561273FE116BQ38212376-7B33AE3E-08C0-4D7C-B035-498D65873240Q38287127-D05C243B-A033-4A93-B57B-21541F4709ABQ38926128-21D2EAB5-86D7-4AA7-AA29-28AFA2BDDBABQ41911306-CA98CF63-7F58-4619-A16F-5A92ECB5D3C5Q41941144-CF412A09-5F22-4C5E-99E1-C5D20328BDD0
P2860
Inhibitors of monoacylglycerol lipase, fatty-acid amide hydrolase and endocannabinoid transport differentially suppress capsaicin-induced behavioral sensitization through peripheral endocannabinoid mechanisms.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Inhibitors of monoacylglycerol ...... al endocannabinoid mechanisms.
@en
Inhibitors of monoacylglycerol ...... al endocannabinoid mechanisms.
@nl
type
label
Inhibitors of monoacylglycerol ...... al endocannabinoid mechanisms.
@en
Inhibitors of monoacylglycerol ...... al endocannabinoid mechanisms.
@nl
prefLabel
Inhibitors of monoacylglycerol ...... al endocannabinoid mechanisms.
@en
Inhibitors of monoacylglycerol ...... al endocannabinoid mechanisms.
@nl
P2093
P2860
P1476
Inhibitors of monoacylglycerol ...... al endocannabinoid mechanisms.
@en
P2093
Andrea G Hohmann
Jessica M Spradley
Josée Guindon
P2860
P304
P356
10.1016/J.PHRS.2010.03.007
P577
2010-04-21T00:00:00Z