Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.
about
Inherited colorectal cancer syndromesEssential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophyThe superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms.Cancer risks for MLH1 and MSH2 mutation carriers.Subtle mutations in the SMN1 gene in Chinese patients with SMA: p.Arg288Met mutation causing SMN1 transcript exclusion of exon7.Three novel missense germline mutations in different exons of MSH6 gene in Chinese hereditary non-polyposis colorectal cancer families.Performance of clinical guidelines compared with molecular tumour screening methods in identifying possible Lynch syndrome among colorectal cancer patients: a Norwegian population-based studyGenetic susceptibility to non-polyposis colorectal cancer.Clinical challenges in management of familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer.Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype.Distinct clinical features associated with microsatellite instability in colorectal cancers of young patients.Hereditary colorectal cancer: risk assessment and management.Current status of linkage studies in hereditary prostate cancer.Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progressionCurrent clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers.Muir-Torre phenotype has a frequency of DNA mismatch-repair-gene mutations similar to that in hereditary nonpolyposis colorectal cancer families defined by the Amsterdam criteria.In Swedish families with hereditary prostate cancer, linkage to the HPC1 locus on chromosome 1q24-25 is restricted to families with early-onset prostate cancerGuidance on gastrointestinal surveillance for hereditary non-polyposis colorectal cancer, familial adenomatous polypolis, juvenile polyposis, and Peutz-Jeghers syndrome.Prevalence of pathological germline mutations of hMLH1 and hMSH2 genes in colorectal cancer.Genetic testing for colon cancer: joint statement of the American College of Medical Genetics and American Society of Human Genetics. Joint Test and Technology Transfer Committee Working Group.Current and evolving strategies for colorectal cancer screening.Frequency of replication errors in colorectal cancer and their association with family historyMicrosatellite instability-a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with colorectal cancer.Defective structural RNA processing in relapsing-remitting multiple sclerosisFrequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patientsHereditary non-polyposis colorectal cancer: clinical and molecular evidence for a new entity of hereditary colorectal cancer.The germline MLH1 K618A variant and susceptibility to Lynch syndrome-associated tumorsMechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1.Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors.Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences.Hereditary aspects of colon cancerHereditary non-polyposis colon cancerRecently identified colon cancer predispositions: MYH and MSH6 mutations.Optimizing the detection of hereditary non-polyposis colorectal cancer: an update.Contrasting molecular pathology of colorectal carcinoma in Egyptian and Western patientsGenomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach.Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohortsUpdate on Lynch syndrome genomics.Classifying MLH1 and MSH2 variants using bioinformatic prediction, splicing assays, segregation, and tumor characteristics
P2860
Q24628009-4CE4712B-F804-4A21-9D86-A8FB60518F15Q28137718-34719598-EF71-404E-857D-4DC3E3F93B3CQ30352527-EB11C8F0-E1F6-4D5A-90A2-6FD16D805921Q30563768-F62F4A09-96BA-49B0-BE39-183E31009693Q31096071-98919593-CA69-4995-9542-770F3A67B3CAQ33298821-B3ABD977-62D3-458A-982E-E97AC83471B8Q33658603-42FD5480-B989-44FF-B329-D94C6C344A01Q33764029-F482B450-FD5C-4DB5-95FE-85EE55AF885AQ33813997-9AD775F2-FFA7-4E44-BAAF-0A32E73E2560Q33904639-E2D8B44A-3645-4493-BE74-A43CE3944FA8Q33904762-D9B9A1F6-6ADA-403D-916F-EA99AEC251A4Q34012713-F9DF4B0D-04BA-47FA-B1B3-1EC4A2E48E22Q34045183-0AF36799-E267-408B-93B6-B83E2F14E612Q34078544-08A82F92-ED5D-471C-BFFB-9E6C6EBBDE09Q34098053-F42EAF5F-6ECA-4FA0-BB17-19D7BB87379BQ34289520-1F30C2D1-8AAE-48F7-9FEC-2FD6EA030CE5Q34386209-3F69C757-C934-42C0-84C1-D020F2EC1BFDQ34390802-69736CDB-DED9-42EB-9601-56F54ADFE810Q34526950-5067E806-3D48-4018-AC68-8A0E93EAEC04Q34633911-790B9B85-0572-4773-899A-27ABC72FFDE6Q35034265-D8D5680B-783F-40BD-A163-D26F3E050E36Q35148786-2090829D-0815-440F-A637-A4E3790A374CQ35352538-771DF8DD-531A-4629-ACDD-0AE4C036DF4FQ35355631-C44BC2D5-8F8E-45FA-BDEB-30131216F5BCQ35491908-BD2C2C7E-F77E-4779-8409-ED669C9E8AA7Q35594265-A0BDFA89-079E-4D74-8CD4-15DD59C4FC02Q35597944-585A9087-0B35-479D-9847-5DA13ECC4C6FQ35608600-003BAB76-2335-4E52-AE50-B26F8A5AD100Q35619996-247F1951-ECE5-4118-8671-7AD6B2AF9E73Q35748966-41660FD8-BB2A-4BDE-B0E6-AF7BC07CC35CQ35753544-9085BBF8-28ED-4CBE-9574-9684C91B01F1Q36101834-B0C33AEF-52FF-4EB9-9CDA-1A0040BBA0EFQ36198294-47A5A311-7BFA-46D1-976C-8130EEEBD9F1Q36484887-96E37939-7A5E-443B-A2A6-9A4A9CA38E1FQ36510713-360B38B7-BB81-467F-9F73-C845AC56AB0DQ36643467-3B2B4B37-5D48-401B-8ED6-AC80D2AAE422Q36646164-8DA919D4-32B4-410B-8173-8328C63CF20AQ36677899-F41313FF-2011-47EF-A6A5-65A70AD108BAQ36990046-B700B0F3-F10A-49E3-AF95-F8931C24A79BQ37254403-E6A77640-77DB-4325-A141-55C2973CE7FC
P2860
Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Hereditary nonpolyposis colore ...... ismatch-repair-gene mutations.
@en
Hereditary nonpolyposis colore ...... ismatch-repair-gene mutations.
@nl
type
label
Hereditary nonpolyposis colore ...... ismatch-repair-gene mutations.
@en
Hereditary nonpolyposis colore ...... ismatch-repair-gene mutations.
@nl
prefLabel
Hereditary nonpolyposis colore ...... ismatch-repair-gene mutations.
@en
Hereditary nonpolyposis colore ...... ismatch-repair-gene mutations.
@nl
P2093
P2860
P356
P1476
Hereditary nonpolyposis colore ...... ismatch-repair-gene mutations.
@en
P2093
H van der Klift
I van Leeuwen-Cornelisse
M Losekoot
P2860
P304
P356
10.1086/514847
P407
P577
1997-08-01T00:00:00Z