Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms.
about
Physiology of cholangiocytesRegulators of Cholangiocyte Proliferation.Role of cholangiocytes in primary biliary cirrhosis.Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology.Functional and structural features of cholangiocytes in health and disease.Effects of dynamic shear and transmural pressure on wall shear stress sensitivity in collecting lymphatic vessels.Histamine regulation of pancreatitis and pancreatic cancer: a review of recent findings.Recent advances in the morphological and functional heterogeneity of the biliary epitheliumNovel identified receptors on mast cells.Calcium signaling in the liverCalcium signaling and the secretory activity of bile duct epithelia.Histamine and histamine receptor regulation of gastrointestinal cancers.Proliferative effect of histamine on MA-10 Leydig tumor cells mediated through HRH2 activation, transient elevation in cAMP production, and increased extracellular signal-regulated kinase phosphorylation levels.Mechanisms of cholangiocyte responses to injury.Isolation and characterization of hepatic mast cells from cholestatic rats.Inhibition of mast cell-secreted histamine decreases biliary proliferation and fibrosis in primary sclerosing cholangitis Mdr2(-/-) mice.Inhibition of mast cell-derived histamine secretion by cromolyn sodium treatment decreases biliary hyperplasia in cholestatic rodents.Inhibition of Mast Cell-Derived Histamine Decreases Human Cholangiocarcinoma Growth and Differentiation via c-Kit/Stem Cell Factor-Dependent Signaling.Knockout of l-Histidine Decarboxylase Prevents Cholangiocyte Damage and Hepatic Fibrosis in Mice Subjected to High-Fat Diet Feeding via Disrupted Histamine/Leptin Signaling.Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats.Bile duct ligation-induced biliary hyperplasia, hepatic injury, and fibrosis are reduced in mast cell-deficient KitW-sh mice.Knockout of histidine decarboxylase decreases bile duct ligation-induced biliary hyperplasia via downregulation of the histidine decarboxylase/VEGF axis through PKA-ERK1/2 signaling.Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2 mice and human cholangiocarcinoma tumorigenesis
P2860
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P2860
Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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2011年學術文章
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2011年學術文章
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name
Histamine stimulates the proli ...... ependent signaling mechanisms.
@en
Histamine stimulates the proli ...... ependent signaling mechanisms.
@nl
type
label
Histamine stimulates the proli ...... ependent signaling mechanisms.
@en
Histamine stimulates the proli ...... ependent signaling mechanisms.
@nl
prefLabel
Histamine stimulates the proli ...... ependent signaling mechanisms.
@en
Histamine stimulates the proli ...... ependent signaling mechanisms.
@nl
P2093
P2860
P1476
Histamine stimulates the proli ...... ependent signaling mechanisms.
@en
P2093
Anastasia Renzi
Antonio Franchitto
Eugenio Gaudio
Fanyin Meng
Gianfranco D Alpini
Guido Carpino
Hannah E Shine
Heather L Francis
Julie K Venter
Kimberly K Baker
P2860
P2888
P304
P356
10.1038/LABINVEST.2011.158
P50
P577
2011-11-07T00:00:00Z
P5875
P6179
1045296048