A double mutation of Escherichia coli2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphosphate.
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Biosynthesis of isoprenoids in plants: Structure of the 2C-methyl-d-erithrytol 2,4-cyclodiphosphate synthase fromArabidopsis thaliana. Comparison with the bacterial enzymesA Structure-Based Approach to Ligand Discovery for 2 C -Methyl- d -erythritol-2,4-cyclodiphosphate Synthase: A Target for Antimicrobial Therapy †Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessmentBiochemistry of the non-mevalonate isoprenoid pathway.Molecular recognition in chemical and biological systems.Synthesis and evaluation of stable substrate analogs as potential modulators of cyclodiphosphate synthase IspF.2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activityCrystal structure of IspF from Bacillus subtilis and absence of protein complex assembly among IspD/IspE/IspF enzymes in the MEP pathway.
P2860
Q27646906-F87D6611-2598-47D5-87AB-70D17E1EDC08Q27654361-EEECB774-1A1F-45FA-9C09-D4B25753753FQ27681270-1A472952-0F5C-4B63-A8E7-09D0046EB12EQ37899789-299AEA20-97D7-4F24-8382-5EDD69927332Q38335784-FBC0278F-C81A-4D59-BE2A-2055085464E2Q41114726-FEC837F9-4460-4FAD-8DEF-2444B49ED66BQ42127680-6BF3814B-F7D4-4BC5-BEFF-07AD0DABE51EQ50043356-BFEE2EFE-5265-4488-B750-0D099C4F3969
P2860
A double mutation of Escherichia coli2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphosphate.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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name
A double mutation of Escherich ...... of, an isoprenoid diphosphate.
@en
A double mutation of Escherich ...... of, an isoprenoid diphosphate.
@nl
type
label
A double mutation of Escherich ...... of, an isoprenoid diphosphate.
@en
A double mutation of Escherich ...... of, an isoprenoid diphosphate.
@nl
prefLabel
A double mutation of Escherich ...... of, an isoprenoid diphosphate.
@en
A double mutation of Escherich ...... of, an isoprenoid diphosphate.
@nl
P2093
P2860
P1476
A double mutation of Escherich ...... of, an isoprenoid diphosphate
@en
P2093
Lauris E Kemp
Nicola Ramsden
Tanja Sgraja
P2860
P304
P356
10.1107/S1744309105018762
P50
P577
2005-06-30T00:00:00Z