Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor.
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Specific receptor subtype mediation of LPA-induced dual effects in cardiac fibroblastsSelective blockade of lysophosphatidic acid LPA3 receptors reduces murine renal ischemia-reperfusion injury.Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors.Development of a phosphatase-resistant, L-tyrosine derived LPA1/LPA3 dual antagonist.International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature.Lysophosphatidic acid (LPA) and angiogenesis.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsRole of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells.Targeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid.Development of an LC-MS/MS assay to determine plasma pharmacokinetics of the radioprotectant octadecenyl thiophosphate (OTP) in monkeys.Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.Discovery of new G protein-coupled receptors for lipid mediators.Synthesis, pharmacology, and cell biology of sn-2-aminooxy analogues of lysophosphatidic acid.Lysophosphatidic acid (LPA)-induced vasodilator-stimulated phosphoprotein mediates lamellipodia formation to initiate motility in PC-3 prostate cancer cellsThe absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer.The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca2+ -activated large-conductance K+ channels in endothelial cells.Regulation of cell survival by lipid phosphate phosphatases involves the modulation of intracellular phosphatidic acid and sphingosine 1-phosphate pools.Phosphorylation and desensitization of the lysophosphatidic acid receptor LPA1.Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells.Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPALysophosphatidic acid receptor agonists and antagonists (WO2010051053).Lysophosphatidic acid regulates the motility of MCF10CA1a breast cancer cell sheets via two opposing signaling pathways.Bioactivity-guided synthesis of gramine derivatives as new MT1 and 5-HT1A receptors agonists.
P2860
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P2860
Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor.
description
2003 nî lūn-bûn
@nan
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
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2003年论文
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name
Identification of a phosphothi ...... agonist of the LPA3 receptor.
@en
Identification of a phosphothionate analogue of lysophosphatidic acid
@nl
type
label
Identification of a phosphothi ...... agonist of the LPA3 receptor.
@en
Identification of a phosphothionate analogue of lysophosphatidic acid
@nl
prefLabel
Identification of a phosphothi ...... agonist of the LPA3 receptor.
@en
Identification of a phosphothionate analogue of lysophosphatidic acid
@nl
P2093
P2860
P356
P1476
Identification of a phosphothi ...... agonist of the LPA3 receptor.
@en
P2093
Andrew D Schrier
Astrid Eder
Gordon B Mills
Graham J Goddard
James R Erickson
Kevin R Lynch
Koji Bandoh
Kwai Wa Cheng
Renata Jarosz
Shuangxing Yu
P2860
P304
11962-11969
P356
10.1074/JBC.M209168200
P407
P50
P577
2003-01-27T00:00:00Z