Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit.
about
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptorMechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding coreAmino terminal domains of the NMDA receptor are organized as local heterodimersSerine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmissionAntidepressant interactions with the NMDA NR1-1b subunitSrc, a molecular switch governing gain control of synaptic transmission mediated by N-methyl-D-aspartate receptors.Affinity labeling of cysteine-mutants evidences contact residues in modeled receptor binding sites.On the hypes and falls in neuroprotection: targeting the NMDA receptor.Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-D-aspartate receptorAn Immunological Approach to Increase the Brain's Resilience to Insults.N-Methyl-D-aspartate (NMDA) receptor subunit NR1 forms the substrate for oligomeric assembly of the NMDA receptor.Apolipoprotein E4 domain interaction occurs in living neuronal cells as determined by fluorescence resonance energy transfer.Identification of molecular determinants that are important in the assembly of N-methyl-D-aspartate receptors.Expression and characterization of a glycine-binding fragment of the N-methyl-D-aspartate receptor subunit NR1.Delineation of the structural determinants of the N-methyl-D-aspartate receptor glycine binding site.Glutamate functions in stomatal closure in Arabidopsis and fava beanHeteromerization of ligand binding domains of N-methyl-D-aspartate receptor requires both coagonists, L-glutamate and glycine.Large-scale expression and thermodynamic characterization of a glutamate receptor agonist-binding domain.Radioligand binding assays for the glycine site on N-methyl-D-aspartate receptors.Structural model of the N-methyl-D-aspartate receptor glycine site probed by site-directed chemical coupling.Putative NMDA receptors in Hydra: a biochemical and functional study.Structural consequences of D481N/K483Q mutation at glycine binding site of NMDA ionotropic glutamate receptors: a molecular dynamics study.Neonatal toluene exposure alters agonist and antagonist sensitivity and NR2B subunit expression of NMDA receptors in cultured cerebellar granule neurons.Sustained saturating level of glycine induces changes in NR2B-containing-NMDA receptor localization in the CA1 region of the hippocampus.
P2860
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P2860
Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Expression and initial charact ...... spartate receptor NR1 subunit.
@en
Expression and initial charact ...... spartate receptor NR1 subunit.
@nl
type
label
Expression and initial charact ...... spartate receptor NR1 subunit.
@en
Expression and initial charact ...... spartate receptor NR1 subunit.
@nl
prefLabel
Expression and initial charact ...... spartate receptor NR1 subunit.
@en
Expression and initial charact ...... spartate receptor NR1 subunit.
@nl
P2093
P2860
P356
P1476
Expression and initial charact ...... spartate receptor NR1 subunit.
@en
P2093
P2860
P304
19933-19937
P356
10.1074/JBC.273.32.19933
P407
P577
1998-08-01T00:00:00Z